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Page last updated at 06:53 GMT, Wednesday, 5 September 2012 07:53 UK
Today: Wednesday 5th September

Grant Shapps, the newly-appointed Conservative Party chairman, speaks to James Naughtie about his new role and David Cameron's cabinet reshuffle. Michelle Obama has told the Democratic Party convention that her husband is a man voters can trust as he seeks a second term as US president. Also this morning, thanks to advances in neuroscience are we about to find out why we behave as we do and how will it affect us?

We are no longer providing clips of every part of the programme but you will be able to listen via the BBC iPlayer .

Business news with Simon Jack: A six-day working week is the latest idea to revive Greece's shrinking economy as the debt inspectors are back in Athens this week to see whether reforms are on target.

China has urged the US not to meddle in regional disputes, hours before US Secretary of State Hillary Clinton began a two-day visit to the country. Bronwen Maddox, editor of Prospect Magazine, gives her analysis of the relationship between China and America.

Business news with Simon Jack.


Developments in imaging technology, genetics, brain chemistry and computing raise the prospect of genuine breakthroughs across a range of debilitating neurological disorders, but in all this excitement about the hardware, is there a danger that we lose sight of what's really important? Science correspondent Tom Feilden asks what neuroscience has to say about what it means to be human.


The future of Heritage Open Days, the annual event coming up this weekend when many private buildings are opened up to visitors and other historic sites allow free entry, is at risk as English Heritage is going to stop funding it. Loyd Grossman, chairman of the Heritage Alliance, one of the organisers of the open days, explains the importance of the event.

Sport news Rob Bonnet.

Former Labour cabinet minister James Purnell and his former permanent secretary at the Department for Work and Pensions, Sir Leigh Lewis, discuss the paper they have written for the Institute of Government giving advice to new ministers in the early stages of running a department.

There has been a third night of trouble in North Belfast, following sustained rioting on Sunday and Monday nights, which the police say was started by Loyalists and when more than 60 police officers were injured. Andy Martin reported from North Belfast last night. And Prof Peter Shirlow, author of The End of the Ulster Loyalist and Rev Robert Beckett, evangelical minister in Belfast, debate the issue of the tension between Loyalists and Republicans.

The paper review.

Thought for the day with Vaishnav Hindu teacher and theologian Akhandadhi Das.


Fewer than 20% of people who have heart attacks in hospital survive to be discharged across the developing world, according to research published by The Lancet. Dr Jerry Nolan, who works at the Royal United Hospital in Bath and who is a member of the Resuscitation Council, gives his thoughts on what should be done to improve the survival rate.


The departure of Justine Greening as transport secretary in yesterday's government reshuffle is being seen as opening the way for a change of policy as she is a dedicated opponent of expansion at Heathrow Airport. Zac Goldsmith, MP for Richmond Park and opponent to the third runway, shares his thoughts , and

Grant Shapps, the new Conservative Party chairman, gives his reaction to the cabinet reshuffle.


Two of the most familiar voices on Radio Four, Harriet Cass and Charlotte Green, are to leave the network next year. As a tribute, the programme plays a couple of Charlotte's most notorious moments.

Sport news with Rob Bonnet.

The auditors for the Europeans and the IMF are back in Greece to look over the books and say yes or no to the next tranche of money. Today hears from Georgios Papakonstantinou, the Greek Environment minister, explains why this decision from the auditors will shape Greece's future in the eurozone.

Sir Peter Bazalgette is the new chairman of the Arts Council of England, one of the last decisions made by Jeremy Hunt as culture secretary before his move in the reshuffle to health. The BBC's arts editor Will Gompertz analyses the appointment.

Supernovae are some of the most dramatic events in the universe and life on this planet would be impossible without them but until now, what drives this process has remained mysterious. Charles Wang, an astrophysicist at Aberdeen University, explains who he came up with a theory which could explain them using an entirely new process.

Business news with Simon Jack.

According to Prof Colin Blakemore of Oxford University, explanations of things we hold dear: love, responsibility, freindship, will come from our greater knowledge of how the brain works in this golden age of neuroscience. Professor Geraint Rees, director of the Institute of Cognitive Neuroscience at UCL and the philosopher Professor Mary Midgley, discuss whether our thinking about freedom, society and culture need to change fundamentally because of new developments in neuroscience.

Matthew d'Ancona, political columnist for the London Evening Standard and the Sunday Telegraph, and Steve Richards, chief political columnist for The Independent, debate David Cameron's cabinet reshuffle.

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