The chairman of the Press Complaints Commission has said that she thinks it is "extraordinary" that Rupert Murdoch asked Rebekah Brooks to lead the News International internal inquiry into phone hacking.
Baroness Buscombe said that she was "deeply unhappy" and "appalled" at being "misled" over phone hacking at the News of the World.
"The corporate culture [at News International] was clearly there to mislead us," she told John Humphrys.
Rather than pinning the blame on the regulator, it was the reporters and executives at the paper who were responsible, she said.
"The blame is clear. I hope you can hear my fury," she said.
The phone hacking scandal had to act as a catalyst for a reform of the British press, she argued.
"Something good has got to come out of this nightmare."
The latest allegation of phone hacking concerns the families of soldiers killed in Iraq and Afghanistan.
Rose Gentle, the mother of a soldier killed in Iraq, said that, if true, the allegations were "pretty disgusting".
Waiting to find out if the allegations are correct, is "like waiting for the knock on the door again," she said.
London Mayor Boris Johnson said the allegations were "deeply, deeply sick" and required an "immediate" judge-led inquiry.
"There's got to be public confidence that this is not just the police washing their own linen," he said.
But he argued against vilifying Rupert Murdoch over the scandal.
"What Rupert Murdoch has done for British journalism
is actually very considerable," he said.
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