PLEASE NOTE: We are unable to offer transcripts for our programme interviews. Today is broadcast live and the running order is subject to change.
A US commuter plane has crashed into a house in the city of Buffalo in New York State. The chief executive of a leading NHS hospital says a new computer system has had a disastrous impact on finances and patient care. And Republican senator Judd Gregg withdraws as President Obama's nominee for commerce secretary, citing policy differences.
A passenger plane has crashed into a house in Buffalo, New York State, with 48 people on board, officials have said. One report said that 44 passengers, four crew and one person on the ground had been killed. Local resident Brendan Biddlecom described the scene.
The civil servant in charge of science at England's universities department has apologised for criticising the new Diplomas as "schizophrenic". A supporter of the new diploma system Deian Hopkin, of South Bank University, discusses why the system has been described as containing a "lack of joined-up thinking".
A new computerised medical records system has been criticised by a leading NHS manager for causing "heartache and hard work". Correspondent Jane Dreaper discusses her interview with Andrew Way, chief executive of London's Royal Free Hospital, who said technical problems had cost the trust £10m and meant fewer patients could be seen.
A third of the Brooklyn Museum's collection of ancient Coptic and Pagan sculptures are fakes. Correspondent Matthew Wells visits the museum to visit their new exhibition - called Unveiling the Truth - which shows off the imitation pieces.
Police in the Australian state of Victoria have charged a man with arson. He is accused of starting one of the deadly bushfires that have killed at least 181 people. Correspondent Phil Mercer reports on more than a dozen fires which are still burning, including one near Healesville, 30 miles north-east of Melbourne.
London Mayor Boris Johnson used the f-word 10 times in a short conversation with Labour MP Keith Vaz, the transcript of their telephone conversation taken by Mr Vaz suggests. Daily Telegraph columnist Andrew Gimson and author John O'Farrell discuss if this changes the way we will think about the mayor.
The new US envoy to Afghanistan and Pakistan, Richard Holbrooke, has arrived in Kabul on what is being described as a fact-finding mission. Correspondent Martin Patience and Professor Michael Clarke, director of the Royal United Services Institute, discusses what Mr Holbrooke is hoping to achieve.
Forty-nine people have died after a passenger plane crashed into a house in Buffalo, New York state. Police have said that all the passengers and crew on the Newark to Buffalo flight were killed; one person on the ground is also reported to have died. Rebecca Gibbons, from New York state police, gives the latest update.
Will the apology given to the Treasury Select Committee make a difference to banking culture? Chairman of the committee John McFall and Peter McNamara, former head of Alliance and Leicester, discuss the intense scrutiny the finance sector is now under.
The race known as the "Superbowl of Nascar" - the Daytona 500 - is the most popular motorsport in the US. Correspondent Kevin Connolly examines the pressures on the car firms, now fighting for survival as well as victory as they turn to the US government for assistance.
The papers have reported details about the entertainment enjoyed by civil servants with glee. But is it justified? Lionel Zetter, author of Lobbying, and Matthew Parris, columnist for The Times, examine whether civil servants should enjoy corporate hospitality.
The Sun newspaper reports on the story of Alfie, a 13-year-old boy who has become a father. Dr Mark Hamilton, who presents a Radio 1 phone-in for teenagers, reacts to the news.
America's oldest civil rights organisation has reached its centenary. The National Association for the Advancement of Coloured People (NAACP) was hugely important during the civil rights struggles of the 1960s. Correspondent Matthew Price considers if the arrival of the first black president in the US means there is less need for civil rights organisations.
We need to be realistic about climate change and start "adapting" to its consequences, as well as mitigating its effects, a report from the Institute of Mechanical Engineers says. Author of the report Dr Tim Fox and author Mark Lynas discuss if this view is too fatalistic.
It is the 60th anniversary of Murphy's Law. The law of physics that "everything that can go wrong will go wrong" is being debated at the Brighton Science Festival. Author Rob Eastaway and Dr Julie Coultas, evolutionary social psychologist at the University of Sussex, discuss if it can be true that everyone's queue is always the one that goes the slowest.