PLEASE NOTE: We are unable to offer transcripts for our programme interviews. Today is broadcast live and the running order is subject to change.
Industrial output in Japan has fallen by nearly 10% - the steepest drop in 55 years. The drugs watchdog NICE has changed its mind and is to allow the use of a treatment that can extend the lives of some cancer patients. And hundreds of striking energy workers are due to hold a mass meeting over the use of foreign workers on a construction project at an oil refinery.
Honda is to close its UK base for four months after Friday's shifts are over. More than 3,000 staff will be affected. Some workers at the plant and correspondent Collette Hume discuss if the manufacturer will "safeguard" employment.
NHS advisers in England and Wales have reached a cost-sharing deal with a drug firm to allow use of a bone marrow cancer drug. Dr Steve Schey, a consultant haematologist at Guy's Hospital and chairman of the UK Myeloma Forum, explains why the drugs body NICE has changed its mind.
On the Lake District coast, in the county of Cumbria, stands a lighthouse that has stood silent for two centuries. Nicola Stanbridge visits the composer who has been commissioned to write and record music inspired by the lighthouse and its surroundings to bring the building back to life.
Prime Minister Gordon Brown and Conservative leader David Cameron will speak at the World Economic Summit in Davos. Business editor Robert Peston considers what might be contained in their speeches.
All UK homes should have access to broadband and faster download speeds by 2012, the government has said. Media expert Peter Bazalgette - former chairman of Big Brother creators Endemol - discusses what will be watched on television and computer screens in three years time.
The Sri Lankan army is pressing ahead with its advance against the Tamil Tigers. Correspondent Chris Morris says that Sri Lanka are frustrated that International agencies start expressing concern for humanitarian issues.
At the World Economic Forum in Davos, there is a downbeat mood as the banks struggle with talk of further bail outs and demands to increase lending. Today presenter Evan Davis talks to HSBC head Stephen Green about the future of globalised banking.
At least 800 people demonstrated at the Lindsey Oil Refinery in Lincolnshire after an Italian firm won a £200m contract. Unions said British staff should be doing the work. Correspondent Danny Savage reports from the refinery, where local people are demonstrating, and Derek Simpson, joint leader of the union Unite, discusses if the promise of "British jobs for British people has been broken".
When the novelist Sebastian Barry won the Costa Book award, it was won despite the fact that his book is, according to the judges, "flawed in many ways". Authors William Boyd and AL Kennedy discuss the concept of the flawed masterpiece.
Sir Christopher Frayling, chairman of the Arts Council, leaves his post after five years in the job. He discusses his time in the job and his valedictory lecture at the Royal Institute of Architects.
A topic being discussed at the World Economic Forum in Davos is "neuroeconomics" - a way of explaining how the brain makes decisions. Cognitive neuroscientist Michael Gazzaniga, of the University of California, and neuroeconomist Gregory Burns discuss what the term really means.
American football teams the Pittsburgh Steelers and the Arizona Cardinals are to compete in Super Bowl XLIII. Alastair Kirkwood, managing director of NFL UK, and Stefan Szymanski, professor of economics at Cass Business School, discuss if big sporting events offer anything more than light relief from the doom and gloom of the economy.
After protests at an oil refinery in north east Lincolnshire over the use of foreign workers, reports of similar protests in other parts of the UK have been received. Correspondents David Mcmillan, at a Corus plant on Teesside, and Scotland correspondent Colin Blane explain the current tension in workforces around the country.
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