PLEASE NOTE: We are unable to offer transcripts for our programme interviews. Today is broadcast live and the running order is subject to change.
The first attempt to re-create the beginning of the universe will begin this morning in Switzerland. Andrew Marr is there to mark the event. And Mike Thomson reports from Haiti where the government is struggling to cope in the aftermath of Hurricane Ike.
Business news with Adam Shaw.
UK housebuilder Barratt Developments has confirmed it is cutting more than 1,000 jobs due to the housing slump and the squeeze on mortgage lending. Barratt, which employs 6,700 staff, said it was cutting 1,200 jobs by closing two divisions and merging other parts of its business. Business correspondent Adam Shaw discusses how much trouble the industry is in.
In a little over an hour from now the Large Hadron Collider will be switched on. It will smash particles together with cataclysmic force in the hope of a better understanding of the composition of the cosmos. Science correspondent Tom Feilden reports from Switzerland where the machine is located.
The security situation in Pakistan has been getting much worse in the past few months, and many observers believe it poses a much greater threat to the west in terms of the so-called war on terror even than Afghanistan. Security correspondent Gordon Corera reports on how Pakistan's new president Asif Ali Zardari will be under a lot of pressure from the US to take tough measures.
Kim Jong Il was conspicuously absent from a parade on Tuesday to mark the 60th anniversary of the communist state. A US intelligence official said the reclusive leader may have suffered a stroke. International relations Professor Hazel Smith of Warwick University discusses the growing speculation about the state of health of the North Korean leader.
Following our report yesterday about escapes from medium and low secure mental health hospitals and from escorting staff, we have had scores of emails, many highlighting the tension between the need for therapy and the demands of security. Professor Sue Bailey from the Royal College of Psychiatrists explains how that balance is being met.
An art historian says he has found that painters who made their money specialising in portraits of famous people chose to redress the balance of power by reproducing their own facial characteristics within those of their powerful sitters. The artist Simon Abrahams explains why he calls the practice 'face fusion', and says it is evident as early as the 1600s in the work of Nicholas Hilliard and Isaac Oliver.
Three decades after it was conceived, the world's most powerful physics experiment is ready to be powered up. Engineers will attempt to circulate a beam of particles around the 27km-long underground tunnel which houses the Large Hadron Collider. Presenter Andrew Marr has exclusive access to the site.
Thought for the day with Reverend Dr David Wilkinson, Principal of St John's College, Durham University.
Two councillors from East Riding in Yorkshire are meeting Environment Minister Phil Woolas today to raise their concerns that part of the coastline above the Humber Estuary will be abandoned to the sea if a new flood risk plan comes into force. Councillor Jane Evison and Phil Woolas debate what is being done about rising sea levels.
A judicial review into the death of a lawyer shot dead by police in London is to open at the High Court. Mark Saunders, 32, was shot after a siege during which he fired at police from his £2m house in Chelsea. His sister Charlotte explains why she is going to the high court to raise issues about the investigation into his death.
The President of Haiti is calling for more international aid following four devastating hurricanes which have hit the Caribbean over the last three weeks.
Rene Preval has said his first priority is to get a "flood" of helicopters to help distribute food. Many roads in Haiti are impassable following the recent collapse of several vital bridges. Correspondent Mike Thomson reports from a relief centre in Haiti's capital, Port-au-Prince.
And Haiti's new prime minister, Michele Pierre-Louis, says people displaced and stranded by recent storms are in urgent need of food and water.
She said Haiti had suffered ecological and economic disaster in the wake of four successive storms that left more than 550 people dead. Strong winds and torrential rains over the past month have battered Haiti's already fragile infrastructure.
Mike Thomson will continue to report from Haiti for the rest of the week.
The most ambitious scientific experiment, the Large Hadron Collider, is about to switched on in Switzerland. The aim of the machine is to recreate conditions moments after the big bang in the hope of better understanding the composition of the cosmos. Andrew Marr and Science Correspondent Tom Feilden are both in Geneva ready to watch the giant machine being switched on.
UK housebuilder Barratt Developments has confirmed it is cutting more than 1,000 jobs due to the housing slump and the squeeze on mortgage lending. Michael Coogan of the Council for Mortgage Lenders and housing expert Henry Pryor discuss the evidence of the downturn in the housing market.
Business news with Adam Shaw.
CEOs of the world's great companies are at the top of the pile. They earn a fortune, wield enormous power and if they do eventually get the sack they can console themselves with massive pay-offs and big pensions. A new book 'The secrets of CEOs' says that is not entirely accurate. One of the authors, Steve Tappin, and Polly Toynbee of the Guardian, discuss the scourge of big business.
Scientists in Geneva have switched on the Large Hadron Collider. Andrew Marr examines what happened.
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