They will want to get their three points in the bag against South Africa, giving them the option of losing against Spain and still being able to make it into the second round by beating Slovenia.
Maldini has a selection dilemna on the left side of his midfield - and how it is resolved should shed some light on his intentions against South Africa.
Jorge Campos is a flying left winger. Extreme pace makes "Campitos" well suited to the counter attacking game.
His selection would be an indication that Maldini is stressing patience, that he wants to draw the South Africans forward and hit them on the break.
Guido Alvarenga is a very different type of player. "The Wizard" is
physically lightweight, but has a wonderfully subtle left foot which could serve as an important supply line for strikers Cardoso and Santa Cruz.
His selection might indicate that Maldini is keener to take the initiative, to bring his team further up the field and have the majority of the possession.
It may not be an easy decision, but it is exactly for his experience in such matters that Paraguay placed Maldini in charge of their World Cup campaign.