The Kuala Lumpur Games were their first, and they sent three athletes to Malaysia to compete.
Several sprint athletes from the island are on scholarships in the USA but cycling is also a popular sport.
Did you know?
Out of their team of five in Manchester, Anguilla has sent three cyclists with Kris Pradel, and brothers Ronnie and Charles Bryan all making the trip.
The trio, who will compete in the 47km road time trial and 187km road race, are working full-time to pay for their equipment.