The FA Vase takes centre stage this weekend, with AFC Blackpool and Squires Gate meeting in a Lancashire derby in the second qualifying round.
As the Premier Division club, Gate will start as favourites against their near neighbours who are still searching for their first win of the season.
Colne, who have lost just once in their last five games, travel to face Holker Old Boys.
Ramsbottom, on the back of a good win in midweek, face Worsborough Bridge.
On Sunday, Bacup Borough will look to build on their fine win in the FA Cup last weekend when they head to Cheshire to take on a Runcorn Linnets side who beat Padiham in the last round.
In the Vodkat League Premier Division, Nelson remain Lancashire's highest-placed team, and they will be looking to bounce back from a home defeat last week when they make the trip to Formby.
A tough assignment awaits AFC Fylde, who visit a Newcastle Town side at the top of the table with five wins and a draw from their six games so far.
In Division One, after notching up their first win of the season last week, Darwen will be looking to make it two in a row away at Chadderton.
After three straight defeats, Padiham will be looking for their first win in a month when they visit Irlam.
Fixtures:
FA Vase Second Qualifying Round
AFC Blackpool v Squires Gate
Holker Old Boys v Colne
Runcorn Linnets v Bacup Borough (playing Sunday)
Worsborough Bridge Athletic v Ramsbottom United
Vodkat League Premier Division
Formby v Nelson
Newcastle Town v AFC Fylde
Vodkat League First Division
Chadderton v Darwen
Irlam v Padiham
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