Serena Williams gets the action under way on Arthur Ashe Court and sees off Yung-Jan Chan 6-1 6-3.
Tournament favourite Kim Clijsters wastes no time in demolishing Martina Muller 6-1 6-2.
Rafael Nadal has little trouble against Bobby Reynolds but still gets pumped up with a 6-3 6-3 6-4 win.
Ekaterina Bychkova causes the first major shock with victory over defending champion Svetlana Kuznetsova.
Kuznetsova is left to ponder another defeat in a difficult year.
Australian fans try and forget about cricket by cheering on Nicole Pratt against Akiko Morigami.
The night session gets off to a spectacular start on Arthur Ashe Court.
John McEnroe (r) causes one of the day's major surprises by duetting with blues legend Bo Diddley.
Maria Sharapova had been expected to struggle against Eleni Daniilidou but powered through 6-1 6-1.
Andre Agassi gives the New York crowd what they want with a 6-3 6-3 6-1 win over Razvan Sabau.