Murray will now head to Shanghai for the upcoming Masters 1000 event
Andy Murray's hopes of success in Beijing came to an end as he was beaten 6-3 6-2 by Ivan Ljubicic in the quarter-finals of the China Open.
The top seed failed to earn a single break point in the match as he went out in one hour and seven minutes.
Ljubicic goes on to face David Ferrer in the last four, while Novak Djokovic will play qualifier John Isner.
"I just didn't hit the ball that well and made quite a few mistakes," said world number four Murray.
"If you're playing against someone who is serving well and you make a lot of mistakes on your own service game, it puts a bit more pressure on you, so that was probably it."
Murray had not dropped a set en route to the quarter-finals but, having saved one break point in the fourth game, he was broken by Ljubicic in the sixth before the Croatian sealed the set with his sixth ace.
At the start of the second set Murray was broken again, and when he did sense an opportunity at 0-30 on the Ljubicic serve his 31-year-old opponent, the world number 17, promptly sent down four aces in succession.
That appeared to deflate Murray and the 23-year-old Scot was broken again as Ljubicic moved through to a semi-final encounter with eighth seed Ferrer, who upset Sweden's third seed Robin Soderling 6-2 6-4.
Defending champion Djokovic secured his place in the semi-finals by beating Gilles Simon 6-3 6-2.
The world number two broke three times and defended all seven break points to beat Simon for the fifth time in a row, and he will now play John Isner after the American beat fourth seed Nikolay Davydenko 7-6 (7-4) 6-4.
It is the fourth time in his last five tournaments that Djokovic has reached the last four, and he was satisfied with his progress after concluding the win over Simon in an hour and 25 minutes.
"I'm very happy that my serve is getting better and better and hopefully, I'm going to use it more and more," the 23-year-old said.
He was rather less enamoured about the conditions in Beijing, however, and said: "The bad air obviously does irritate you a little bit, especially if you're playing against somebody that you expect to play long rallies with.
"We had so many long rallies and it's hard to recover when you don't have fresh air.
"A box of oxygen or something on the bench would be great, but we don't have it. I guess I will have to get used to it."
The ATP said they would look into the air quality concerns.
Djokovic beat Isner in their only previous encounter in March, but took more than four hours and six match points to defeat the 6ft 9in American in Davis Cup action.