Tsonga lost the Australian Open final to Novak Djokovic
Australian Open runner-up Jo-Wilfried Tsonga has been forced to pull out of the French Open due to a knee injury.
Frenchman Tsonga had been seeded 14th at Roland Garros for this year's tournament, which starts on Sunday.
He will have surgery on his right knee next week and will miss Wimbledon, the Olympic Games and possibly the US Open.
"After long discussions with my doctors and knee specialist, I made the decision not to play the French Open and to have surgery," said Tsonga.
"It's enormously frustrating. To play very well in any Grand Slam is super, but to play very well at Roland Garros would have been magic."
Elsewhere Germany's Nicolas Kiefer and Italy's Fabio Fognini have also been forced to withdraw through injury.
The pair were replaced in the main draw by Marc Lopez of Spain and Josselin Ouanna of France while Tsonga will be replaced in the draw by Luis Horna of Peru.