Fernando Gonzalez became the latest seed to fall at the Australian Open as he was outplayed by Croatia's Marin Cilic in their third-round clash.
Gonzalez was a shadow of the player that reached last year's final
Gonzalez, seeded seventh and last year's runner-up, had no answer to the big serving of 6ft 5in Cilic.
The 19-year-old was always in control as he claimed the biggest win of his career, 6-2 6-7 (4-7) 6-3 6-1.
He next meets James Blake, who came back from two sets down for the first time to beat Sebastien Grosjean.
American Blake, seeded 12th, came through a pulsating encounter 4-6 2-6 6-0 7-6 (7-5) 6-2 to make the last 16.
Third seed Novak Djokovic motored into the fourth round with an easy 6-3 6-1 6-3 over Sam Querrey.
The Serbian, who meets Lleyton Hewitt or Marcos Baghdatis next, took just over an hour-and-a-half to see off the unseeded American.
It just seemed like every time there was a mountain to climb
The match was played under the retractable roof on Vodafone Arena as rain disrupted the schedule.
And Blake fought back from 4-1 down in the third set and 5-3 down in the tie-break to seal a magnificent win.
"That's got to be my biggest comeback," Blake said. "It just seemed like every time there was a mountain to climb.
"I played so well to kind of get myself out of trouble in the fourth set there, I wasn't going to lose that momentum and let it go the other way.
"That was a good feeling."
With rain continuing, the only other early men's match to start saw Gonzalez take on Cilic under the roof of the Rod Laver Arena.
And Cilic, who had never won a Grand Slam match before this year's Australian Open, was thrilled to keep his run going.
"It was probably the best match of my life," said the 19-year-old. "It was fortunate we were playing indoors, it helped me with my serve without the wind."
Gonzalez, who had pulled himself back into the match by winning the second-set tiebreak, blamed illness and injury for his exit.
"I wasn't at 100% but I was able to play," the Chilean said. "I was fighting a lot.
"I got here like 15 days ago, and after three, four days it started to bother my shoulder because the ball was too heavy, and I was really tired.
"In the last two days had a stomach upset, so I couldn't take it anymore. I was really disappointed."