Arvind Parmar's surprise run in the Rotterdam Open ended when he was beaten 6-3 6-3 by Belgium's Christophe Rochus in the quarter-finals.
Parmar earned his first Tour win since June 2004 in his first match
Parmar, who was in the tournament as a lucky loser after Rafael Nadal's withdrawal, was the last Briton in the event after Tim Henman's defeat.
Rochus broke twice in the first set and Parmar was treated for an abdominal problem at the start of the second.
Another break to go 3-1 up proved enough for Rochus to see off Parmar.
"I've had a stomach pull over last few days," said the Briton. "It affected my serve but not my groundstrokes.
"I'm a bit disappointed that I couldn't do better, but this has still been a really good week for me."
Despite the defeat, it was a good week for British number five Parmar, who was ranked 230th in the world at the start.
He beat Paradorn Srichaphan in round one and then overcame Dominik Meffert to earn his clash with Rochus and the chance to reach an ATP semi-final for the first time in his career.
Parmar made a good start with a brilliant backhand lob which landed just inside the baseline in his first service game but was soon under pressure.
He saved one break point in the fifth game before conceding it to Rochus and although he broke back immediately, the Belgian broke again to love and went on to win the set.
Parmar hit back from 0-30 down to hold in his first service game of the second set but Rochus again dictated play.
Although Parmar had a break point in the fifth game he failed to take it and the Belgian secured his place in the last four.
Russia's Nikolay Davydenko reached the semi-finals with a 6-4 6-2 win over Daniele Bracciali.
He faces Radek Stepanek next after the sixth seed beat Tim Henman's conqueror Novak Djokovic 7-5 4-6 7-6 (7-2).