World number one Roger Federer required only 71 minutes to book his place in the third round of the Nasdaq-100 Open with a 6-3 6-1 win over Olivier Rochus.
Federer powered 12 aces to brush aside the diminutive Belgian, who beat the tour's tallest player, Ivo Karlovic, in the opening round.
Six-times champion Andre Agassi began his 19th Nasdaq-100 Open campaign with a 7-5 6-4 win over Paul-Henri Mathieu.
The 34-year-old shrugged off worries about his injured toe.
"I felt it a little bit but when I pushed through it never got worse, so that was reassuring," said Agassi.
"It was a tough match. There's nothing I take for granted out there, especially not these days, and it was a good one to get through."
Elsewhere, 10th seed Joachim Johansson was beaten in straight sets by unseeded American Jeff Morrison.
Nicolas Kiefer lost out in the all-German clash, beaten comfortably 6-4 6-2 by Florian Meyer.
Victor Hanescu took the opening set with ease against Taylor Dent but had to concede the match through injury whilst trailing 4-0 in the decider.
Last year's runner-up Guillermo Coria safely negotiated his opening match against Davide Sanguinetti, beating the Italian 6-1 6-4.
Argentina's Coria had to retire from last year's final against Andy Roddick with back pains caused by kidney stones.
Roddick retired from the tournament on Friday with a wrist injury.