Greg Rusedski will hope to maintain the form he showed in Britain's Davis Cup defeat of Israel in the first round at Indian Wells on Friday.
The British number two, who won both his singles matches in Tel Aviv without dropping a set, faces American qualifier Jeff Salzenstein.
A good run in the Masters Series event will boost the 31-year-old's hopes of returning to the world's top 20.
Fellow Briton Tim Henman has a bye in the first round.
The sixth seed will play highly-rated 15-year-old Donald Young or a qualifier in round two.
Henman is under pressure to defend 350 ranking points after making the final last year before losing to Roger Federer.
1. Roger Federer
2. Lleyton Hewitt
3. Andy Roddick
4. Marat Safin
5. Guillermo Coria
6. Tim Henman
7. Carlos Moya
8. Gaston Gaudio
9. Andre Agassi
10. David Nalbandian
But the Briton is in confident mood after his early-season injury worries.
"My back has been so much better over the past few weeks or so," Henman told his website.
"I've got a few days to get used to the conditions but hopefully it won't take me that long as I enjoy playing here.
"The ball travels through the air a bit quicker and that suits my game."
Henman is in the same half of the draw as Federer and Safin, while Rusedski has Andy Roddick, Joachim Johansson and Carlos Moya in his quarter.