A brilliant display by Olivier Mutis sent second seed Andy Roddick crashing out of the French Open in Paris.
The little-known Frenchman, ranked 125 in the world, dug deep to shock the American, winning 3-6 6-3 6-7 6-3 6-2.
Roddick looked comfortable in the first set, but began to struggle in the second which the Frenchman took.
The American won a tie-breaker and looked to be back on track, but Mutis refused to give up and Roddick began to lose his form, before crashing out.
The cool, damp conditions appeared to sap some of the power of Roddick's devastating serve.
He hit 15 aces but lost his serve nine times in a match that lasted more than three hours.
Roddick admitted he only had himself to blame for his shock defeat.
"I wasn't decisive enough. I wasn't sticking with things I wanted to do," the American said after the match.
"He was a different player the latter part of the match than he was at the beginning. It was my fault that I let him back into the match," he said.
Roddick's loss means no American male player will be left in the third round, which has never happened in any Grand Slam tournament in the open era.