Former champion Andre Agassi produced a devastating display to sweep aside Armenia's Sargis Sargsian and reach the last eight of the US Open.
The 34-year-old American set the pace of the match, quickly opening up a 2-0 lead in the first set which he took 6-3 before racing to the second 6-2.
There was no way back for Sargsian, who received treatment on a knee injury, as Agassi rattled off the third set 6-2.
Agassi now faces Swiss Roger Federer in a hotly-anticipated quarter-final.
The world number one had a walkover into the last eight after his fourth round opponent Andrei Pavel withdrew with a back injury.
The Romanian has been beset by wrist and back problems since last April and did not want to aggravate his injuries further in New York.
"It was a very big risk that if I played it could be much, much worse
and danger my career," said Pavel. "So I don't want to do that."
The 16th seed's decision to pull out gives Federer a spot in the quarter-finals for the first time in five appearances at Flushing Meadows.
Federer, who has won three of the past five Grand Slams, has only dropped one set in the tournament.
Agassi looked back to his best as he raced to victory over his close friend Sargsian in exactly 90 minutes.
The 1994 and 1999 champion stormed to seven straight game to go 4-0 up in the third set before sealing victory with a powerful forehand.
"I never expect to win easily," Agassi insisted.
"Sarg hasn't won four matches for no reason, I just wanted to take care of business."
Dominik Hrbaty will meet Britain's Tim Henman in the last eight after he overcame Olivier Rochus in an engrossing encounter.
The Slovakian 22nd seed came back from two sets down to see off the Belgian 2-6 3-6 6-3 6-4 6-0.
Rochus looked to be on course for a place in the last eight but his game came unstuck when he picked up an injury.