Slovakia's Daniela Hantuchova has withdrawn from the Paris Open because of breathing problems.
Hantuchova's form has slumped in recent months
Hantuchova overcame France's Sandrine Testud in the first round but said she had been suffering from a cold.
Her second round opponent, French 16-year-old Tatiana Golovin will now face second seed Elena Dementieva of Russia in the quarter-finals on Friday.
Former champion Mary Pierce of France beat Spain's number eight seed Magui Serna 6-2 6-4 to reach the next round.
Top seed Kim Clijsters raced into the quarter-finals by beating Spaniard Maria Sanchez-Lorenzo 6-0 6-1.
The match lasted only 39 minutes.
Russian Elena Bovina
dispatched Serbian fourth seed Jelena Dokic 4-6 7-6 (7/5) 6-0.
And Switzerland's Patty Schnyder, the third seed, lost out to Dinara Safina 4-6 6-2 6-1.
Safina also beat Schynder en route to her first WTA title at Sopot in 2002.
Safina will meet Italian fifth seed Francesca Schiavone for a place in the
Schiavone was made to work before coming away a 7-6 (7/4) 6-3
winner against Croatia's Karolina Sprem.
Former Paris champion Mary Pierce brushed aside
eighth-seeded Spaniard Magui Serna in straight sets to advance to
the last eight.
Pierce took the tie on her fourth match point to win 6-2 6-4 after an hour and 19 minutes.
Italy's Francesca Schiavone, seeded fifth, progressed to the last eight with a 7-6 (7-4) 6-3 win over Karolina Sprem of Croatia.