Scotland head coach Frank Hadden has excluded lock Scott Murray from a 35-man Six Nations training squad.
Murray won his 87th Scotland cap during last year's World Cup
The record cap holder fails to keep his place after the World Cup, while centre Marcus Di Rollo, prop Craig Smith and hooker Scott Lawson are also left out.
Uncapped Edinburgh quartet Ross Rennie, Calum MacRae, Ben Cairns and Nick De Luca are called up, along with Glasgow winger Thom Evans and prop Moray Low.
Hadden confirmed Jason White would continue as Scotland captain.
"Jason is a key figure for us," said Hadden. "He sets the tone as a leader both on and off the field and I look forward to working with him again during this season's Championship."
Centres Rob Dewey and Andrew Henderson will attend the squad gathering on 14 January despite carrying injuries, as will Stade Francais number eight Simon Taylor, who has a thumb problem.
However, Northampton winger Sean Lamont is out for the rest of the season with knee ligament damage.
Di Rollo has made the decision to make himself available exclusively for Toulouse during the tournament but has stressed that he will battle for a place thereafter.
The centre has managed just one minute of game time since his post-World Cup move to France from Edinburgh.
"Making myself unavailable for Scotland for this year's Six Nations Championship was not a decision I took lightly," he said.
"After a period of injury and transition from Scotland to France I felt it would be beneficial for my game to take some time to settle in to my new club."
Centre Cairns, 22, is listed in the squad for the first time, while Ulster winger Simon Danielli returns after missing the World Cup through injury.
"I continue to be impressed with the competition for places in the squad," added Hadden.
"A number of players have maintained their good form from the World Cup but they are going to be pushed extremely hard by some of our young, up and coming talent in the next few weeks."
Scotland will kick off their campaign at home to France on 3 February, while England also visit Murrayfield.
Murray, now playing in France with Montauban, won his 87th cap in the World Cup defeat to New Zealand, having first been called up as a teenager in 1996.
But Hadden insists he is not closing the door on the 31-year-old.
"There is hot competition for places in the second row," he told BBC Sport.
"We know what Scott can bring to the table, so let's see how much progress the younger players can make.
"I had a good long chat with Scott and he made it very clear that he is still excited about the possibility of playing for Scotland."
Scotland squad for training at Murrayfield on 14 January:
Backs: Mike Blair, Ben Cairns, (both Edinburgh), Chris Cusiter (Perpignan), Simon Danielli (Ulster), Nick De Luca (Edinburgh), Thom Evans (Glasgow Warriors), Phil Godman (Edinburgh), Rory Lamont (Sale Sharks), Rory Lawson (Gloucester), Calum MacRae (Edinburgh), Graeme Morrison, Dan Parks (both Glasgow), Chris Paterson (Gloucester), Hugo Southwell (Edinburgh), Nikki Walker (The Ospreys), Simon Webster (Edinburgh)
Forwards:John Barclay, Johnnie Beattie, Kelly Brown (all Glasgow), Dave Callam (Edinburgh), Alasdair Dickinson (Gloucester), Ross Ford (Edinburgh), Jim Hamilton (Leicester Tigers), Nathan Hines (Perpignan), Allister Hogg, Allan Jacobsen (both Edinburgh), Alastair Kellock (Glasgow), Gavin Kerr (Edinburgh), Moray Low (Glasgow Warriors), Scott MacLeod (Llanelli Scarlets), Euan Murray (Northampton Saints), Ross Rennie (Edinburgh), Alasdair Strokosch (Gloucester), Fergus Thomson (Glasgow), Jason White (Sale Sharks)
Injured but invited to the training session: Andrew Henderson (Glasgow), Simon Taylor (Stade Francais), Rob Dewey (Ulster).