France have called up Montferrand winger David Bory to their World Cup squad to replace the injured Xavier Garbajosa.
Bory has won 16 international caps
Bory - who had been on stand-by after coach Bernard Laporte left him out of the original 30-man squad - is expected to join the French camp in Sydney on Tuesday.
Garbajosa will fly home from the World Cup after failing to recover from a knee injury in time to play in the tournament.
He missed France's opening two games - against Fiji and Japan - with a thigh injury and returned to training this week but was forced onto the sidelines after suffering sharp knee pain while running.
It is the same knee which was operated on for cartilage damage in July.
"We are saying goodbye with a heavy heart," said France team manager Jo Maso.
"We spoke to Bory's coach and he said that he is on top form. Xavier has been getting a lot of pain in training and is not 100%.
"If Xavier had been older we may have taken a risk, but he is young enough to play in another World Cup, so the best thing is for him to go back to France and see the physios who treated him after the original operation.
As a tribute, Maso and coach Bernard Laporte invited him to hand out the shirts before France's game against Scotland.
"It was a very moving gesture. I'm of course very disappointed but I can't cheat," Garbajosa said.
"I can't run at full speed and it was demoralising not to be in top form. I prefer to leave my place to a player who will be 100% fit.
"From now on, I shall be the first supporter of the team."
Maso also revealed scrum-half Fabien Galthie (ankle) and Tony Marsh (Achilles) both picked up minor knocks in the 51-9 win over Scotland and are unlikely to be considered for the final Pool B outing against the USA on Friday.