Fijian fly-half Waisale Serevi and flanker Alivere Mocelutu have been ruled out of the World Cup because of injury.
Serevi injured himself 10 minutes into the Japan game
Serevi came off just 10 minutes into the 41-13 win over Japan on Thursday with a shoulder complaint.
An X-ray later revealed he had suffered a broken collarbone, while Mocelutu is out with a fractured right forearm.
The news is a massive blow ahead of the Fijians' must-win game against Scotland on 1 November.
The Pacific Islanders must beat the Scots to keep alive any hopes of qualifying for the quarter-finals.
There are also doubts over the fitness of scrum-half Sami Rabaka, who broke a small bone in his right hand against the Japanese.
But Rabaka will play if necessary against the Scots.
"This is very disappointing for the whole squad," a team spokesman said.
"The core of the team has been together for a long time and to lose two players like this is disappointing for everyone."