All the action from the Pool C match in Brisbane.
80 mins: Pastore has a chance for another Uruguayan score as an England pass goes awry. But as he tries to gather his own kick ahead and knocks it forward. It paves the way for the final whistle.
78 mins: Worsley is sin-binned and rightly so for a totally unnecessary high tackle. Pastore is the man who takes the blow around his neck.
76 mins: The ball dances through the hands of backs and forwards alike and once again it's that man Lewsey who is on hand to run the try in. Remarkably it's his fifth of the night.
England 111-13 Uruguay
73 mins: The century mark is finally cleared as Catt runs in under the posts. He has Bracken to thank for it, having sent him on his way.
England 106-13 Uruguay
70 mins: Robinson again is on hand for another sharp run. He side-steps Campomar and, with determination etched all over his face, outruns his challengers to sprint 70 metres in for the score.
England 99-13 Uruguay
68 mins: Robinson breaks the Uruguayan shackles and, as the ball is recycled, Greenwood breaks two tacklers for his first try of the night. Catt gets the conversion.
England 94-13 Uruguay
66 mins: England give Uruguay's try line a bit of respite as a night of all-out running begins to take its toll.
63 mins: Greenwood replaces Grayson, so Catt moves to number 10 for England. Kyran Bracken also enters the fray in place of Gomarsall. Both replaced half-backs have enjoyed good games.
59 mins: Arguably the simplest try of the night and Gomarsall scores it. He looks back startled as no one comes near him and has to chuckle at the ease of it all.
England 87-13 Uruguay
57 mins: England get ever closer to the 100-point mark as Lewsey fends off his tacklers for try number four.
England 80-13 Uruguay
54 mins: Robinson, on for the injured Balshaw, touches down under the posts and once more it's all thanks to some good handling. Grayson unleashes a perfect pass to Catt, who in turn pops it to Robinson. No one comes close to stopping him.
England 73-13 Uruguay
52 mins: Lewsey's solo charge seals his hat-trick. Quick passes by Grayson and Catt send him on his way.
England 66-13 Uruguay
49 mins: Uruguay's try celebrations are short-lived as Abbott sprints in for the second England try of his brief international career to date. Two right-footed side-steps see him through.
England 59-13 Uruguay
48 mins: Diego Lamelas nearly scores from a Uruguayan line-out but stumbles just short of the line. But Pablo Lemoine is on hand to score from the resulting break, taking Danny Grewcock with him in the process. Menchaca converts.
England 52-13 Uruguay
45 mins: Balshaw is stretchered off with an ice pack on his right ankle. It looks serious. Robinson comes on. Martin Corry is also replaced, Martin Johnson moving into the second row.
44 mins: Luger adds his name to the try scorers. He jigs past his first two tacklers, sprints down the line and then hands off Menchaca to touch down.
England 52-6 Uruguay
42 mins: Try one takes no time at all - Lewsey getting his second. Joe Worsley does the damage, sprinting clear before looping a delightful one-handed mis-pass to Lewsey. Grayson misses his first conversion.
England 47-6 Uruguay
41 mins: Sebastian Aguirre gets the game restarted. As usual, Dallaglio takes it and sets up the first England attack.
40 mins: Dallaglio fails to let go of the ball and Uruguay get a penalty. Menchaca goes for it and over it goes on the stroke of half-time.
England 42-6 Uruguay
39 mins: Gomarsall is a deserving try scorer. He has looked sprightly all night and just manages to ground the ball after delving through the Uruguay defence.
England 42-3 Uruguay
37 mins: From another quick line-out, England show some sleak handling and running. They win a penalty for their efforts, because of Uruguayan off-side.
34 mins: England score the try of the night so far, courtesy of Mike Catt. Gomarsall goes for a quick line-out on his 22. Balshaw darts clear, pulls off a lovely one-two with Lewsey before sending Catt on his way.
England 35-3 Uruguay
32 mins: After 10 phases of recycled Uruguayan ball, England finally win it back from a Juan Campomar knock-on.
29 mins: Remarkably England are still camped deep in England territory as their rivals continue to push for the try line. For the time being, the English defence is stout but it's captivating viewing.
26 mins: Uruguay's forwards come within a whisker of scoring as England's pack capitulates. But in the final moment, they knock it forward.
24 mins: Uruguay win big applause after opting for a line-out after being awarded a kickable penalty. Dallaglio is penalised a moment later and the referee threatens to sin-bin him if he errs any more.
22 mins: Try number two from Balshaw, who this time looks bewildered at the lack of tackling from the opposition. England seem to have found their stride. A monster boot by Paul Grayson helps the cause.
England 28-3 Uruguay
21 mins: Immediately from the re-start England are quickly off their blocks again, this time Mike Catt making the yards. But Uruguay's defence temporarily steadies.
19 mins: Uruguay fluff their re-start and England win a put-in. From the resulting scrum, Iain Balshaw sprints past the startled south Americans.
England 21-3 Uruguay
17 mins: England win a scrum in front of the Uruguayan posts. Andy Gomarsall pings it to Josh Lewsey, who hands off his opposite number for his ninth international try.
England 14-3 Uruguay
14 mins: Mike Catt, Joe Worsley and Stuart Abbott all have a go on the break with varying degrees of success. But play is stopped abruptly when Joaquin Pastore clashes heads with Abbott. He looks alright though.
12 mins: Lawrence Dallaglio is penalised for playing the ball on the ground. Menchaca gets another penalty chance but it goes just wide of the right-hand post.
10 mins: England are far from convincing at the moment. Their latest misunderstanding sees Joe Worsley knock on a Martin Corry pass. Both men try to pass the blame to the other.
8 mins: The Uruguayans seem to be enjoying themselves in the scrums, making England's front three work in the set pieces.
6 mins: Uruguay get themselves on the score sheet as an England infringement is penalised. Juan Menchaca slots over the penalty.
England 7-3 Uruguay
3 mins: Lewis Moody gets try number one of the game. With England dominant from the outset, the ball is spread down the backs and Moody jogs in nonchalantly with players to spare.
England 7-0 Uruguay
0737 GMT: Paul Grayson, Jonny Wilkinson's stand-in for the day, smacks the ball to the Uruguayan forwards which England immediately take for their first attack.
England: J Lewsey; I Balshaw, S Abbott, M Catt, D Luger; P Grayson, A Gomarsall; P Vickery (capt), D West, J Leonard; D Grewcock, M Corry; L Dallaglio, L Moody, J Worsley
Replacements: S Thompson, J White, M Johnson, B Kay, K Bracken, W Greenwood, J Robinson
Uruguay JM Menchaca; J Pastore, D Aguirre (capt), J De Freitas, J Viana; S Aguirre, J Campomar; E Berrutti, D Lamelas, P Lemoine, J-C Bado, J-M Alvarez, N Brignoni, N Grille, R Capo
Replacements: JA Perez, R Sanchez, G Storace, J Alzueta, M Guttierrez, E Caffera, D Reyes