Wasps have switched the opening match of their Heineken Cup defence against Munster on 10 November to Coventry's Ricoh Arena.
Wasps have won the Heineken Cup twice in four years
The London club also moved from Adams Park for their semi-final win over Northampton last season which raised the capacity from 10,000 to 32,000.
"This has the potential to be a very special game," said Wasps director of rugby Ian McGeechan.
"I'm delighted that we're returning to the Ricoh and looking forward to it."