All the action from Rome.
Full-time: Wales banish memories of their defeat at the Stadio Flaminio two years ago, as they run Italy ragged with a six-try performance.
80 mins: Italy attempt to salvage some pride as time ticks away but Wales remain in the ascendency as the whistle goes.
76 mins: Masi makes great ground in the Italian centre to create space for Robertson, who again mistakes the ball for a bar of soap - much to his team-mates' frustration.
74 mins: Play pauses for De Marigny to get treatment for a badly twisted ankle that ends his game, while Martyn Williams makes way in the Welsh back-row for Robin Sowden-Taylor to win his first cap.
73 mins: TRY Wales lock Robert Sidoli, who is of Italian extraction, claims a try in the left corner after great hands from Cooper, Shane Williams and Sweeney, although Henson misses the tough conversion.
Italy 8-38 Wales
69 mins: Orquera floats a fine miss-pass to Kaine Robertson on the Italy left wing, only for the New Zealand-born player to drop the pass in the face of rushing Welsh tacklers.
67 mins: Italy lock Marco Bortolami drives into the midfield and finds Parisse hanging on the left wing, the number eight gallops for the line but Morgan and fresh Wales fly-half Ceri Sweeney gang-tackle him into touch.
64 mins: Gareth Cooper, on as Wales scrum-half, floats a beautiful pass to Gareth Thomas in space on the right, only for the Toulouse man to take his eyes off the ball and drop it.
61 mins: Both sides make a string of changes, but despite some fresh legs Italy, for the first time in the match, are struggling to reach the game line when they attack.
57 mins: TRY Wales are now rampant and produce the best try of the match. Skipper Thomas starts with a break, replacement wing Kevin Morgan applies the pace and his superb off-load sends Shane Williams over for a deserved try, converted by Jones.
Italy 8-33 Wales
55 mins: TRY Shane Williams puts together five jinking sidesteps straight through the heart of the Italy defence, then his Ospreys team-mate lock Brent Cockbain rampages on to claim a converted try.
Italy 8-26 Wales
52 mins: Wales launch a superb break, Shane Williams taking two tackles as he passes to Gareth Thomas, then Henson and Luscombe combining to surge down the right flank to reach the Italian 22.
48 mins: Italy lose open-side flanker Mauro Bergamasco to injury and David dal Maso comes on to replace him.
47 mins: Nitoglia breaks clear as Italy put together a superb period of running rugby that takes them to the Wales line, a try seems imminent but a knock-on denies the Azzurri at the end.
44 mins: PENALTY Prop Andrea Lo Cicero gets Italy rumbling forward and earns De Marigny another penalty kick, which turns out to be third time lucky as it sails over.
Italy 8-19 Wales
43 mins: Shanklin looks to be troubled with a shoulder injury, which isn't improved any as big Italy number eight Parisse barrels into him.
41 mins: Stephen Jones gets the game restarted with a kick deep into the Italy 22.
Half-time: Italy 5-19 Wales
40 mins: TRY Wales finish the half in style as Luscombe cuts back on a fine angle before finding Martyn Williams in support. The flanker touches the ball on the foot of the post and the video referee agrees it is a try. Jones converts with boos from the Italian crowd ringing in his ears.
Italy 5-19 Wales
38 mins: Williams and Owen dice with danger and flipped passes trying to find space and time in their own 22, but Luscombe eventually does the sensible thing to boot the ball upfield.
33 mins: Italy roll the ball upfield in a maul with Aaron Persico and Sergio Parisse to the fore, but when the ball goes wide wing Ludovico Nitoglia hangs onto the ball in the tackle and a good position is lost.
31 mins: Wales' turn to earn a penalty, Henson immediately grabbing the ball for the kick despite it being almost 55 metres from the posts. The direction is good but the ball drops just under the crossbar.
28 mins: The Italy full-back gets a chance to make immediate amends from slightly further back but more central, only to slide this penalty kick across the face of the posts.
27 mins: The Welsh scrum is forced into conceding a penalty but De Marigny hits the near post with his attempt from the 10-metre line.
25 mins: Italy scrum-half Alessandro Troncon apologises to referee Andrew Cole after catching the Australian plum in the ear with his kick.
22 mins: The physicality of the exchanges claims its first victim as Italy centre Andrea Masi limps off with a bloody nose, Matteo Barbini replacing him briefly.
21 mins: TRY Wales have another bite from a reset scrum and go to the backs, Henson kicking to the left corner to find Shanklin jumping highest to gather and score an unconverted try.
Italy 5-12 Wales
20 mins: Wales force a five-metre scrum on the Italy line but a superb scrummage disrupts the visitors.
18 mins: A harmless looking up-and-under from Henson is missed completely by Italy full-back De Marigny and Wales wing Hal Luscombe is just denied a try by the ball bouncing into touch.
17 mins: Ragged period of play sees the two sets of forwards wrestling away in the middle of the park for supremacy, while rush defence from both sets of backs keeps things tight.
14 mins: Wales exert some control with a series of drives from around the ruck, allowing Henson to measure a better kick and pin Italy in their own 22.
11 mins: TRY Gavin Henson makes a clean break but his attempted chip is knocked down by Orquera, who gathers to race away for an Italy try. Roland de Marigny misses the conversion.
Italy 5-7 Wales
10 mins: Italy wing Mirco Bergamasco pulls off a superb cover tackle to haul down Shanklin as Wales threaten to break down the right wing.
7 mins: Fierce tackling causes Italy to turn the ball over and Wales skipper Gareth Thomas gathers to race upfield, there are three players in support inside him but he opts to kick ahead and the chance is lost.
5 mins: TRY Shane Williams fields an Italian kick and bursts through to be hauled down just short of the Italy line, Wales recycle and Michael Owen's long pass finds flanker Jon Thomas in space on the left to score. Stephen Jones converts.
Italy 0-7 Wales
2 mins: Wales show early adventure as they stretch the Italians first left and then right, before Tom Shanklin's grubber kick turns the home defenders.
1335 GMT: Italy fly-half Luciano Orquera kicks off to get the match started under grey Roman skies.
Wales attempt to build on their opening victory over England as they seek to avoid a repeat of the defeat suffered in Rome two years ago.
Despite losing blind-side flanker Dafydd Jones to injury, the promotion of Jonathan Thomas is the only change to the visitors' starting side.
Italy, who beat Wales 30-22 at the Stadio Flaminio in 2003, tested RBS Six Nations title chasers Ireland to the limit last week.
Walter Pozzebon comes in for injured centre Gonzalo Canale as the Azzurri aim for only their fourth Six Nations victory.
Italy: R de Marigny; Mirco Bergamasco, W Pozzebon, A Masi, L Nitoglia; L Orquera, A Troncon; A Lo Cicero, F Ongaro, M Castrogiovanni, S Dellape, M Bortolami (capt), A Persico, Mauro Bergamasco, S Parisse.
Replacements: G Intoppa, S Perugini, CA del Fava, D dal Maso, P Griffen, M Barbini, KP Robertson.
Wales: G Thomas (capt); H Luscombe, T Shanklin, G Henson, S Williams; S Jones, D Peel; G Jenkins, M Davies, A Jones; B Cockbain, R Sidoli; J Thomas, M Williams, M Owen.
Replacements: R McBryde, J Yapp, I Gough, R Sowden-Taylor, G Cooper, C Sweeney, K Morgan.
Referee: Andrew Cole (Australia).