England swept to their sixth successive win over South Africa to maintain their early momentum under Andy Robinson.
Charlie Hodgson starred with a try in a 27-point personal haul, equalling the English record against the Springboks.
The fly-half, after missing five kicks against Canada, responded with a 100% record while Mark Cueto also crossed to give the hosts a 20-6 half-time lead.
South Africa could only manage three Percy Montgomery penalties until a late try from replacement Bryan Habana.
After seeing their Grand Slam dream die in Dublin last week, this was another humbling defeat for the Tri-Nations champions.
Number eight Martin Corry and flanker Lewis Moody were outstanding as England's back row comprehensively outplayed their vaunted Springbok counterparts.
And Hodgson furthered his claims for Jonny Wilkinson's jersey with another assured display, one late missed tackle apart.
England were on the scoreboard inside the first minute after Springboks lock Victor Matfield rushed up to clatter Hodgson and was adjudged offside.
The fly-half duly stroked over the penalty, but the hosts were fortunate not to concede a try in the fifth minute when De Wet Barry went straight through Henry Paul's tackle.
But fortunately for the rugby league convert, Barry lost the ball with an overlap beckoning.
The Springboks drew level when Cueto found himself isolated on the right flank and was penalised for holding onto the ball, Montgomery's kick scraping over.
Hodgson celebrates his opening try
But after a couple of strong bursts from Corry, England seized the initiative with an opening try from Hodgson after 15 minutes.
Steve Thompson and Andy Gomarsall combined to release the fly-half into space and he held off the tackles of Jean de Villiers and Breyton Paulse to score at the posts.
Hodgson's conversion made it 10-3 and within 10 minutes England had taken command with another quality try.
The impressive Josh Lewsey weaved his way past four tacklers, Hodgson continued the move and Paul's perfectly-judged cross-kick sailed straight into the arms of the waiting Cueto.
Hodgson slotted the conversion from wide out.
Montgomery did reduce the deficit after Moody infringed at a ruck but Hodgson's third penalty gave England a commanding 20-6 interval lead.
South Africa hinted at a comeback with Montgomery's third penalty on the resumption, but it was quickly cancelled out by Hodgson.
The England fly-half completed his own personal 'full house' with a smartly struck drop-goal after strong forays from Mike Tindall, Joe Worsley and Corry.
Scrum-half Harry Ellis was introduced for his Test debut and two more Hodgson penalties, in the 58th and 70th minutes, should have seen England cruise home from 32-9.
But Jaco van der Westhuyzen beat Hodgson's tackle to send replacement Springboks wing Habana scorching over with seven minutes left.
South Africa finally started to open up and threatened more tries, but it was all far too late.
England: J Robinson (capt); M Cueto, H Paul, M Tindall, J Lewsey; C Hodgson, A Gomarsall; G Rowntree, S Thompson, J White, D Grewcock, S Borthwick, J Worsley, L Moody, M Corry.
Replacements: A Titterell, A Sheridan, B Kay, A Hazell, H Ellis, W Greenwood, B Cohen.
South Africa team: P Montgomery; B Paulse, M Joubert; De Wet Barry, J de Villiers, J van der Westhuyzen, F Du Preez; O Du Randt, J Smit (captain), E Andrews, B Botha, V Matfield, S Burger, AJ Venter, J van Niekerk.
Replacements: H Shimange, CJ van der Linde, D Rossouw, G Britz, M Claassens, J Fourie, B Habana.
Referee: Alain Rolland (Ireland)