Worcester tumbled out of the European Challenge Cup at the first hurdle after a 40-10 mauling by Brive on Saturday.
CHALLENGE CUP RESULTS
Borders 107-3 Coimbra
(Borders win 205-6 on agg)
Saracens 36-10 Bayonne
(Saracens win 60-31)
Leeds 17-18 Grenoble
(Grenoble win 27-26)
Brive 40-10 Worcester
(Brive win 53-39)
Connacht 40-21 Narbonne
(Connacht win 51-46)
London Irish 42-18 Auch
(London Irish win 62-36 )
Sale 50-3 Catania
(Sale win 81-25)
The Zurich Premiership new-boys took a 14-point lead into the second leg but that vanished after barely 20 minutes.
The home side led 25-3 at half-time, with Worcester's only points coming from a James Brown penalty goal.
They did manage a converted try from former Springbok Thinus Delport but 25 points from wing Julien Laharrague saw the hosts cruise home.
Worcester became the second English club to fall after Leeds' exit on Friday.
A last-minute try from Jason Tiatia gave Grenoble, coached by former Leicester boss Dean Richards, an 18-17 win at Headingley and a 27-26 aggregate victory.
The three other English sides all progressed with comfortable victories.
Sale Sharks romped to a 50-3 win over Italian minnows Catania at Edgeley Park on Sunday.
Centre Chris Mayor scored two of the Sharks' seven tries to book a second round date with 'lucky losers' Narbonne, who lost out to Irish province Connacht.
Connacht overturned a 14-point first-leg deficit with a convincing 40-21 win at home, fly-half Paul Warwick scoring two tries in a 22-point personal haul.
London Irish will also play French opposition in the next round in the shape of Pau after putting Auch to the sword at the Madejski Stadium.
Full-back Delon Armitage scored two of the Exiles' six tries as they led 35-6 at the break before easing to a 42-18 victory.
Saracens progressed on Friday with a comfortable 36-10 victory over Bayonne, a Richard Haughton hat-trick of tries helping secure a 60-31 aggregate win.
They will next face Italian club Overmach Parma, who overturned a 24-point deficit against Spanish outfit El Salvador to squeak through by two points.
El Salvador lock Carlo Del Fava was red-carded for over-vigorous rucking and
later suspended from all rugby for 10 weeks.
Clermont Auvergne (formerly Montferrand) will provide stern opposition for Scottish side Borders after back-rower Elvis Vermeulen scored a hat-trick of tries in a 51-6 crushing of Italian side Leonessa.
Borders destroyed Portuguese minnows Coimbra 107-3 (205-6 on aggregate) on Friday.