Shaw only lasted five minutes against Ireland
England lock Simon Shaw has been ruled out of Saturday's Calcutta Cup match with Scotland at Murrayfield because of a shoulder injury.
Shaw picked up the injury during the 20-16 Six Nations defeat by Ireland at Twickenham on 27 February.
Gloucester centre Mike Tindall has been called into the squad by national manager Martin Johnson.
England are still awaiting news on the fitness of full-back Delon Armitage, who has a rib cartilage injury.
"Delon's rib injury is difficult to call when he will be fit," said Johnson last week.
Wasps star Shaw, 36, went off in the first five minutes of England's defeat last Saturday.
On Friday the results of an MRI scan revealed he had suffered no additional damage to his left shoulder and that the injury was confined to the acromioclavicular joint.
Shaw was replaced against Ireland by Leicester lock Louis Deacon, who is favourite to start against Scotland.
Tom Palmer has also been called into the squad as an injury replacement for Shaw.
Northampton full-back Ben Foden, who came on for the last half-hour against Ireland, joined England's training camp at Pennyhill Park last Tuesday and is a likely replacement for Armitage.
Olly Morgan has also been called into the squad and the Gloucester full-back could be on bench if Armitage is not fit, with Foden starting.
Johnson kept his starting XV plus Deacon, Foden and Bath tight-head prop David Wilson in camp last week.
That number included James Haskell - despite demands from his club Stade Francais that he return for a Top 14 match last Saturday - but the flanker was unable to train because of a stomach bug.
Northampton back Shane Geraghty has also been called up as a precaution as cover for Leicester's Toby Flood, who took a knock on his head over the weekend playing for his club
The rest of the bench from the Ireland game - Paul Hodgson, Toby Flood, Lee Mears and Joe Worsley - and the 10 elite squad members who were not involved against Ireland were released to play with their clubs last weekend.