Result: ENGLAND 42-20 SCOTLAND
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1750 GMT: England skipper Vickery reaches the top of the Twickenham staircase, receives the Calcutta Cup from the Princess Royal and raises it aloft. Scotland, meanwhile, cannot improve their record of four victories in 96 years at Twickenham.
80 mins: Late flurry from Scotland, running the ball from deep, but the final whistle blows and England have handed Scotland a pretty comprehensive defeat. Phenomenal performance by Wilkinson, fine performance by his halfback partner Ellis, and Farrell was solid, if understated on debut. Scotland were game, but were seriously outmuscled up front and outclassed behind the scrum.
79 mins: Ellis, who has been superb all match, goes on another foray but is hauled down just short. Wilkinson has been named man-of-the-match, and you can't really argue with that.
76 mins: England 42-20 Scotland
Dewey with a try for Scotland, selling Tindall the dummy and crashing over between him and Farrell. Bit easy for Scotland, but they're certainly not lying down. Paterson kicks the extras.
75 mins: There is an Interactive Forum at 1800 GMT on BBC Interactive - press your button to get involved after the match.
74 mins: Flood on for Wilkinson and the Newcastle fly-half is awarded a standing ovation by the Twickenham faithful. That was some comeback. England skipper Vickery off for White.
73 mins: England 42-13 Scotland
Woeful defending by Scotland, Ellis simply whipping the ball wide from the scrum to Lund and the Sale flanker ducking over unopposed. Three Scotland defenders were hovering around the scrum, none of them spotted him. Schoolboy. Wilkinson misses with the extras.
71 mins: Farrell setting up a ruck like he's been doing it all his life and Wilkinson spoons an attempted drop-goal. He was aware, however, that England had been awarded a penalty and he kicks to touch.
68 mins: Tindall with some adventure, carrying the ball from deep and passing inside to Lund. However, the England flanker throws a sloppy inside pass and the move breaks down.
66 mins: Not a lot going right out back for Scotland, Di Rollo spilling after a tackle by Wilkinson. Lawson on for Cusiter at scrum-half for Scotland. Cusiter, back from injury, played well.
"What a performance by Jonny Wilkinson. He's been excellent with his kicking and distribution. I can't believe he's been away for three years."
Former Scotland fly-half Gregor Townsend
63 mins: Ford replaces Hall at hooker for Scotland.
60 mins: Dewey on for Henderson in the Scotland midfield and Rees, making his England debut, replaces Worsley in the back-row.
58 mins: England 37-13 Scotland
Ellis with another electric break from the base of the scrum, dancing past Cusiter and managing to get the ball inside to Wilkinson. Wilkinson goes over in the corner, but his right foot is in touch...oh no it isn't, the video ref has decided he got it down. Not sure about that one, that looks like a shocking decision. Wilkinson rubs salt into Scottish wounds with a pearling kick from the sideline.
56 mins: Scotland make a change, Jacobsen on for Kerr in the front row.
54 mins: England 30-13 Scotland
Corry gathers a poor Scottish throw at the line-out, Ellis hacks through and Lamont makes a hash of things, failing to smother the ball and Robinson plundering his second try of the game. Wilkinson, from the left touch-line, dumps over the extras.
53 mins: England 23-13 Scotland
Another infringement by Scotland and Wilkinson gets another go from the 10-metre line. Slotted again, and Scotland are clinging on for dear life now. Scotland need to speed things up and show some adventure here.
"Can you ask Austin Healey why he is dressed like Margot from the Good Life?"
48 mins: England 20-13 Scotland
Wilkinson with a chip-through and Cusiter just manages to gather. Good sweeping move by England, Wilkinson slipping the ball to Worsley and the flanker just unable to offload. Farrell then shows some good distribution skills, sending the ball wide to Morgan and the full-back just being hauled down on the left wing. However, Wilkinson is on hand to slot three points after a Scotland infringement.
42 mins: England 17-13 Scotland
Parks gets the second half under way and Farrell shows another string to his bow with a big left-footed punt to touch. Good move by the Scottish backs though, Paterson slipping a weak Tindall tackle on the left flank and Scotland earn a penalty. Paterson strikes it sweetly from the 10-metre line and the Scots are right back in the mix.
"It's probably quite a good result for Scotland so far but I'd like to see Parks do more than just kick away possession. They can't play for the next 40 minutes in the same way."
Former Scotland international Andy Nicol
"It's as if Wilkinson's never been away, although I'd like to see Wilkinson take control a little bit more."
Former England centre Jeremy Guscott
"Sitting in a bar in Dubai watching the match, outnumbered by Scots fans and being drowned out by a very happy band of French suppoters celebrating the trouncing of Italy. Great atmosphere though."
Half-time: Fascinating first 40 minutes, England starting well and finishing in thunderous fashion and Scotland scrapping well throughout. One thing is certain: Jonny Wilkinson, with three penalties and a drop-goal, is back.
38 mins: Another sparkling break from Ellis straight from the scrum and the Leicester number nine is having a very good game so far.
36 mins: England 17-10 Scotland
England's first try, the backs shovelling the ball down the back-line, Robinson selling the dummy and dancing over in the corner. Wilkinson misses with the extras. Fine off-load by Wilkinson in that move as well and he looks in fine fettle so far.
33 mins: Robinson fields an attempted clearance and we get the first glimpse of Farrell as a runner, breaking the first tackle as England swarm towards the Scotland line. However, Chuter dives over the top and Scotland get the penalty. Not clever by the England hooker.
30 mins: England 12-10 Scotland
Better by England, stringing some phases together at last. Ellis with a nice break and England get the penalty after what might have been a high tackle on Farrell. Wilkinson hasn't lost his touch, and he kicks the three points. Unerring stuff by the bloody England fly-half.
29 mins: England 9-10 Scotland
Corry is taken out at the line-out and Scotland are punished by the boot of Wilkinson.
27 mins: Farrell with the miss-pass and Lewsey making something of nothing, breaking the tackle and Callam having to put in a sturdy tackle.
23 mins: England 6-10 Scotland
Parks sends down a good, probing kick that carries beyond Robinson and dribbles into touch and Taylor scores from the resulting line-out. Paterson slots the extras and it's no more than the Scots deserve at this stage. Very sloppy from England, Deacon with a flap-back and Ellis completely missing the ball. The sun hasn't quite come up on Ashton's new dawn so far.
20 mins: Morgan is tested by a dirty great Garryowen and the young Gloucester full-back is found wanting, almost missing the ball completely. Scotland might look to mine that option for the rest of the match. Robinson is then skinned by Parks and Scotland are more than holding their own so far.
19 mins: England 6-3 Scotland
England hit back immediately, Worsley turning Parks in the tackle from the restart and Wilkinson slotting a drop-goal. Haven't seen that for a while.
17 mins: England 3-3 Scotland
Blood streaming from one of Wilko's orifices, difficult to tell which one. Scotland get another penalty as an England player fails to roll away from a ruck and this time Paterson is spot on with a straightforward kick.
14 mins: More indiscipline from England gives Scotland their first penalty of the match. Poor from Corry, taking Callam out at a line-out. But Paterson, the most successful goalkicker in the world last year, pushes it wide.
12 mins: England's pack rumbling away, looking to grind down the Scots, but a little bit of nonsense from Deacon in the ruck gives the visitors some breathing space.
9 mins: England 3-0 Scotland
England get a scrum bang centre and in front of the Scottish try-line and the Scots concede a penalty. Here's Jonny! Wilkinson slots an easy penalty, but the Scots will perhaps be relieved not to have conceded more than three points.
8 mins: England go for the shove but Scotland's pack holds firm and Ellis cannot control at the base of the scrum. Drop of blood on Wilkinson...but it's nothing serious. Hallelulah time for England fans.
7 mins: Chuter shows and goes, full-back Morgan breaks the line on the left flank and Ellis crashes over the line. The referee goes to the television official, but it looks like Paterson may have held him up. Indeed, the England scrum-half failed to ground the ball, but nice inter-change between forwards and backs by England.
6 mins: Moral victory for England, shoving the Scottish pack five yards down towards their try line. The English scrum will be looking to beast the Scots into submission in this first half.
4 mins: Spot of argy-bargy in the front row, Vickery taking exception to something said or done. He'll be chomping at the bit, desperate to stamp his authority on this having inherited the captain's armband from number eight Corry.
3 mins: Ellis sets Grewcock free down the right flank but Lund is unable to take a low pass around his knees. Should have picked that up. Slow from England.
2 mins: Wilko decides to run the ball but is held up by Di Rollo. Farrell then gets his hands on the ball for the first time, passing inside to his old Wigan team-mate Robinson.
1 min: Referee Jonker blows his whistle and Wilkinson makes contact with a ball for England for the first time since the World Cup final in 2003. We're off and I, for one, am quite excited.
1559: Flower of Scotland booms around Twickenham and it sounds as though there are plenty of Scots in town. God Save The Queen is sung with some gusto by the England players. One player particular is getting very carried away. Can't locate him, but he sounds like that keeno you get at every wedding.
1556: Scotland emerge from the tunnel and are left to wait while England get themselves ready in the tunnel. The hosts are led out by Tindall, Corry and skipper Vickery - all playing the 50th game for England.
"I just don't see where the tries are coming from Scotland, they lack a cutting edge."
Former Scotland international Andy Nicol on BBC One
1554: "Did you know that after it was damaged a few years ag, the Calcutta Cup was restored to its former glory by my granddad, Robert Lamb from Mexborough, who is now in his 50th Year of silversmithing!"
Toby Warburton (aged 8)
1549: "It's 7.45am here in San Francisco and I've just thrown my girlfriend out of bed and told her she needs to drive me across town to get to the pub to watch the match live. It's a new dawn for English Rugby! I'm shouting as she throws some shoes on. Go England...don't start without me."
1548: "There is a huge crowd of us sat in front of the TV at the Moris pub in Val d'Isere, France. We had to come in early from skiing to get the seats so we're still sat here in our ski boots...we're not missing this game!"
Nick, Adam, Lucy, Max, Rick, Fraser, Harry, Abi, Becky, Al, Charlie, Tom
1545: "It is not a medical gamble to play Jonny. The gamble is he has not had any rugby behind him."
Former Scotland captain Andy Nicol
1540: "It has been so long since Jonny Wilkinson played for England that in 2003 he had leaders all around him - Martin Johnson, Lawrence Dallaglio, Matt Dawson, Will Greenwood, Mike Tindall - calling the shots. But now he has come back he needs to take this team to places they need to go - ans that is winning games."
Former England centre Jeremy Guscott
1533: Less than half an hour to go to kick-off now. Jeremy Guscott, Andy Nicol and Jonathan Davies - dubbed "the voice of reason" by John Inverdale - have taken their place in the BBC studio.
1530: "I am in Lecce in the south of Italy. Italy struggled today, but now I am supporting England!"
1520: "Sitting in an office in a compound in El Obeid, Sudan, waiting for the match. I will have to follow on the internet so it will be a little frustrating. Sudan is DRY so the first Calcutta Cup for me without a beer since my very early teens!"
Mark B in Sudan
1518: "Yes, it's back! The Six Nations is, with all due respect to the World Cup, THE great tournament for us. Great moments. Great memories. Every match has pride and passion riding on it."
Mark Kidger at the Villafranca del Castillo Satellite Tracking Station Madrid
1515: "God only knows how I'm going to see the game here in Lima, but here's hoping that we can revive some of that 2003 spirit."
Michael in Peru
1512: "Am sat here in Western Australia waiting for the match to start with my webcam pointed at my parent's telly in the UK. Improvised technology at its best...come on England! We can't lose to the Scots at Twickenham."
Dan in Australia
1508: The Scotland locks, James Hamilton and Alastair Kellock, have apparently swapped shirt numbers. Maybe a ploy by Hamilton to confuse his Leicester team-mate Louis Deacon, one of his opponents today?
BBC Sport's James Standley
'Hi Brian off-shore in Azerbaijan. I'm a very proud Cornishman on-shore in Baku, watching the BBC net and cheering on England led by a fellow Cornishman. Come on England!"
Steve, Baku, Azerbaijan
"I'm in Kyoto currently trying to find somewhere to watch the Calcutta Cup. Unfortunately the Japanese do not seem to realise how important it is!"
Dan, Kyoto, Japan
"I'm sitting here on an offshore oil rig in Azerbaijan, watching the BBC Website on my computer. I think Scotland will do the business today, Come on Scotland!"
Brian, Baku, Azerbaijan
"Even though I'm thousands of miles away, I'm off to O'Malleys to watch the game in the only Irish pub in town. My passion for English Rugby is no less and I expect our boys to be more passionate that ever and beat the Scots comfortably. Let's hope Jonny puts his shooting boots on!"
Chris Coates, Sao Paulo, Brazil
"We are a bunch of English students in the heart of Scotland at St Andrews University. We are quietly confident of an English revival but the Scots will be outnumbering us at the pub so it will be nerve-wracking, whatever the result!"
Chris, Johnny, Ross and Nick (St Andrews, Fife)
Gearing up to go to Tigin's pub in Stamford, CT, to watch the game with some English friends. Guinness and full Irish breakfast awaits. Hoping for another Scotland win, but nervous about Ashton's impact on England.
Keith Bowie, Old Greenwich, CT, USA
"We are three Scots cowboys working out on the range and waiting to take a break to catch the Calcutta Cup. Hope it will be a good match with the proper ending. Go Scotland!"
L&DS & KP, Madera, California
"Spare a thought for Ed Baylis (English) and Stu Turnbull (Scottish), currently attempting to row across the Atlantic (www.atlantic06.com). They have a whole Jaffa Cake riding on the outcome of today's Calcutta Cup. The stakes could not be higher!"
"Just walking through the gates I can feel the atmosphere already and I am really excited about coming here again.
It is going to be really exciting with Wilkinson playing, and Vickery leading from the front. I am full of expectation.
The bigger the stage, the better Andy Farrell plays and I think he will do very well today."
Former England coach Andy Robinson, interviewed in the BBC studio at Twickenham.
"Just at home now watching Italy v France! I really hope for a Scotland win today. My three closest mates are English and if we lose my life will be misery for a few weeks! Come on the Scots!!
Stevo J, Inverness
"I'm sat at work watching the BBC text commentary. I think England will win today, but I'm still nervous. Come on England!"
"I've seen hordes of very hairy-legged men in kilts spilling off the trains from Waterloo into Twickenham station. It can only mean Scotland are in town for the start of a new Six Nations season. They are being accompanied by thousands of gleaming white shirts proudly sported by England's optimistic followers. They hope to see the dawn of a new winning era under coach Brian Ashton. We wait to see."
BBC Sport's James Standley
1400 GMT: Just two hours to go now until the big kick-off at Twickenham. Are you at the game, in the pubs around the ground, out and about or just at home watching Italy v France and waiting for the action to begin?
Why not let us know where you are, how you think the game will go and what you have spotted on your way to the match or wherever you are going to watch it.
England: Morgan; Lewsey, Tindall, Farrell, Robinson; Wilkinson, Ellis; Freshwater, Chuter, Vickery (capt), Deacon, Grewcock, Worsley, Lund, Corry.
Replacements: Mears, White, Palmer, Rees, Richards, Flood, Tait.
Scotland: Southwell; S Lamont, Di Rollo, Henderson, Paterson (capt), Parks, Cusiter; Kerr, Hall, E Murray, Kellock, Hamilton, Taylor, Callam, Brown.
Replacements: Ford, Jacobsen, S Murray, Hogg, Lawson, Dewey, R Lamont.