Huddersfield are to lodge an official complaint with the Rugby Football League claiming discrimination.
The Giants are upset Jamahl Lolesi was charged with striking during Sunday's defeat at Leeds although he has since been cleared by an disciplinary panel.
They were also angry prop Keith Mason was banned after a clash with Leeds' Jamie Peacock in a pre-season friendly.
"We believe our players are being discriminated against," said Giants football manager Stuart Sheard.
"We are asking disciplinary commissioner Norman Sarsfield to investigate the actions of the video review panel and we have a bank of evidence to support our argument."
Lolesi was found not guilty of striking by an RFL disciplinary panel on Tuesday.
The Giants are currently bottom of Super League after losing all four of their opening matches.