Warrington (36) 82
Tries: Bridge 3, Briers, Solomona 2, Myler, Evans, Westwood 2, Morley, Blythe, Mitchell, Hodgson Goals: Hodgson 13
Harlequins (6) 6
Hodgson ended Warrington's rout with 30 points
Warrington broke a club record as they served up a stunning 14-try thrashing of previously in-form Harlequins.
A Chris Bridge treble, Lee Briers, David Solomona and Richard Myler put the Wolves in charge at the break, Luke Dorn going over for Quins.
Rhys Evans, a second from Solomona, Ben Westwood, skipper Adrian Morley, Matty Blythe and Lee Mitchell made it 72-6.
Westwood then grabbed his second before Brett Hodgson, who ended with 13 goals, went over to take Warrington top.
Tony Smith's men now lead by a point from unbeaten champions Wigan, who have a game in hand.
Warrington's incredible margin of victory was not quite enough to secure a new Super League record, set by Bradford Bulls in 2000 when they trounced Salford 96-16.
But they became only the fourth team in the 16 seasons of Super League history to score more than 80 points in a game.
And, given that Quins had won four of their previous five games this season, and had won at Leeds and St Helens on their two previous away outings, this was an astonishing result.
Smith's men opened their account inside six minutes when Myler and Briers combined to allow Bridge in at the far corner. He then doubled his tally eight minutes later after being put through by Hodgson.
Quins' defence was breached for a third time when Myler gave Briers the space to run clear from 20 metres out.
Hodgson then sent Bridge through for his hat-trick before Dorn went over from close range to give the visitors their only score of the match, converted by Luke Gale.
But, if Quins thought they were about to stage a fightback, Wolves destroyed their hopes when Solomona touched down from close range before Myler capitalised on another defensive lapse.
Warrington continued their dominant performance after the break as Evans raced through to add a seventh try four minutes after the restart.
Solomona went over to claim his second before Briers sent Westwood crashing over the line.
Morley made it 60-6 within an hour as his outstretched arm was enough to ground the ball and an 11th try was added soon after by Blythe.
Solomona then put Mitchell through and Westwood grabbed his second as he waltzed through the Quins defence, Hodgson missing with the boot for the only time.
But the Warrington full-back soon made up for his missed attempt, going over for the final score of the afternoon, to which he added his 13th conversion.
Warrington assistant coach Willie Poching:
"We prepared ourselves to play against a tough team and Quins were that at the start of the game.
"Things just didn't go their way, but we started to get a roll on and get them on the back foot. That's hard to recover from and things got a bit out of hand for them.
"Quins will recover from this. It's only a blip and Rob Powell is doing a great job."
Harlequins coach Rob Powell:
"That was a very good Warrington side and by far the best performance I've seen in terms of skill, ability and executing a game-plan.
"Warrington were really good but that doesn't excuse us conceding over 80 points and not being good enough.
"We're obviously not as good as what people thought we were. That was us playing very badly and Warrington playing very well on the same day."
Warrington: Hodgson; J Monaghan, Blythe, Bridge, Evans; Briers, Myler; Carvell, M Monaghan, Wood, Grix, Westwood, Harrison.
Replacements: Morley, Clarke, Solomona, Mitchell.
Harlequins RL: Dorn; Melling, Howell, Pryce, O'Callaghan; Gale, Randall; Ward, Ellis, Wilkes, Clubb, Purdham, Bailey.
Replacements: Bryan, Ambler, Koupartisas, Temata.
Sin Bin: Ward (56).
Ref: Steve Ganson (St Helens).