Reanne Evans is aiming to become the first woman to win four successive World Snooker Championships.
The 22-year-old from Dudley is the current world number one, despite winning only one ranking event so far this season.
"Cambridge has been a good venue for me, I would love to remain world champion because that's the best you can be," Evans said.
Fellow Dudley player Maria Catalano enters the tournament ranked fourth.
Catalano is the cousin of former men's world champion Ronnie O'Sullivan and has had to take time off from her father's ice-cream business in the Black Country.
She has already won the British Open and the Connie Gough National Championship this season.
Evans is convinced that Catalano will be a major threat, along with Kent's Katie Henrick, June Banks, and Emma Bonney from Portsmouth.
"Although there are some very good players such as Maria, June, Emma and Katie, I still feel confident enough in my game to win," Evans added.