The 21st Breeders' Cup takes place in Grande Prairie, Texas, on Saturday.
The Breeders' Cup is run at a different track each year
With eight races all carrying at least $1m in prize money, the US meeting has become one of the highlights of the Flat season.
For the first time, it is being staged in the south-west of the United States.
Over 50,000 spectators will be watching the event at the Lone Star Park track, which is just seven years old.
Race schedule (all times BST)
1820 BREEDERS' CUP DISTAFF
Distance: 1m 1f
2003 winner: Adoration (P Valenzuela) 40-1
Distaff means the female side of the family and so this race is only open to fillies and mares.
Nebraska Tornado, representing champion French trainer Andre Fabre, is the only European challenger.
1855 BREEDERS' CUP JUVENILE FILLIES
Distance: 1m ½f
2003 winner: Halfbridled (J Krone) 7-4 fav
US jockey Julie Krone made history last year, becoming the first female rider to win a race at the Breeders' Cup.
European hopes in this year's contest are pinned on Aidan O'Brien's Mona Lisa while Frankie Dettori will be partnering US-trained Sharp Lisa.
1935 NETJETS BREEDERS' CUP MILE
Distance: One mile
2003 winner: Six Perfections (J Bailey) 5-1
One of only three races on the card which are run on turf as opposed to dirt, it is therefore unsurprising that European-trained horses have won this race nine times.
Six of those winners have hailed from French stables, including the past two years.
Last year's winner Six Perfections is aiming to retain her crown and is joined by two other French-trained horses - Diamond Green, who will be ridden by Frankie Dettori, and Whipper.
Meanwhile, Irish trainer Aidan O'Brien has sent over Antonius Pius.
2010 BREEDERS' CUP SPRINT
Distance: Six furlongs
2003 winner: Cajun Beat (C Velasquez) 14-1
There are no European challengers for the shortest race on the card.
Favourite for the sprint is likely to be Kela, who is trained in California by Mike Mitchell.
2045 V05 BREEDERS' CUP FILLY & MARE TURF
Distance: 1m 2f
2003 winner: Islington (K Fallon) 10-3 Fav
The turf race provided a European clean sweep last year as Sir Michael Stoute's (GB) Islington came home ahead of L'Ancresse and Yesterday, both of whom came from Aidan O'Brien's stable in Ireland.
Yesterday goes again this year but and is joined by dual Oaks winner Ouija Board.
Trained by Ed Dunlop, Ouija Board will be ridden by Kieren Fallon, who will be wearing the famous colours of the filly's owner, Lord Derby.
2120 BESSEMER TRUST BREEDERS' CUP JUVENILE
Distance: 1m ½f
2003 winner: Action This Day (David Flores) 20-1
Aidan O'Brien enjoyed his first Breeders' Cup triumph in this race three years ago with Johannesburg and the Irish trainer is aiming for another geographically-themed success this year with Scandinavia.
Also running is Wilko, who is trained in England by Jeremy Noseda and who will be ridden by Frankie Dettori.
2155 JOHN DEERE BREEDERS' CUP TURF
Distance: 1m 4f
2003 winner: Deadheat between High Chaparral (M Kinane) 11-2 and Johar (A O Solis) 20-1
Last year saw high drama as 2002 champion High Chaparral came across the line level with Johar, sparking the first-ever dead-heat in Breeders' Cup history.
Powerscourt carries High Chaparral's trainer Aidan O'Brien's hopes for a hat-trick, and it would also be the fourth year in a row the race has been won by a British or Irish challenger.
2235 BREEDERS' CUP CLASSIC
Distance: 1m 2f
2003 winner: Pleasantly Perfect (A Solis) 14-1
The blue riband event of the card offers a huge first prize of over $2m (£1.1m).
No British or Irish horse has ever won and that duck will not be broken this year as there are no European challengers.
However, Frankie Dettori, who has never won a Breeders' Cup race on dirt, rides the Japanese-trained Personal Rush.
Pleasantly Perfect is looking for back-to-back Classic victories - since winning last year the six-year-old has also claimed the Dubai World Cup and is reported by trainer Richard Mandella to be better than ever.
Another runner is Freefourinternet - formerly trained in the UK by Brian Meehan - who will be ridden by female jockey Greta Kuntzweiler.