Since taking out her licence in 1989, Knight has built up a stable full of quality horses.
Date of birth:
15 December 1946
Started training: 1989
Base: Wantage, Oxfordshire
Festival wins: 5
2001-2002 wins: 48
2000-2001 wins: 39
1999-2000 wins: 42
Main jockey: Jim Culloty
Stable stars: Best Mate, Edredon Bleu
A former biology teacher, Knight's equine career began in the world of eventing.
This has undoubtedly influenced her approach to training, which complements the more hard-headed expertise of her assistant trainer and husband, former champion jockey Terry Biddlecombe.
Knight's first Cheltenham winner came with Karshi, owned by her brother-in-law (and chairman of Cheltenham racecourse) Lord Vestey.
But much of her success has come from horses owned by Jim Lewis, who made contact after reading an article about her in a magazine.
He has provided her with several of her Cheltenham Festival winners - two coming from the evergreen Edredon Bleu who won the Grand Annual in 1998 and a thrilling Champion Chase in 2000.
But it is Best Mate for whom Knight, Biddlecome and Lewis will surely be remembered in years to come.
Best Mate has already secured two Cheltenham Gold Cup wins and a King George VI Chase. Few would bet against the tally increasing.