Miller could not add a fourth gold medal to his Paralympic haul
Britain's Stephen Miller went down to his first ever Paralympic final defeat after finishing second in the men's club throw final at the Bird's Nest.
The 28-year-old defending champion had been unbeaten for 12 years until Tunisia's Mourad Idoudi won gold with a new world record of 35.77m.
Miller set a new personal best with 34.37m, but had to settle for silver.
Earlier, team-mate Daniel Greaves won a bronze medal in the discus to take GB's overall athletics medals haul to 11.
After gold in Athens, the 25-year-old had been favourite to defend his title, but his best throw of 53.04m was over two metres behind US gold medallist Jeremy Campbell.
Greaves became the first Paralympian to represent Great Britain in an able-bodied event when he was selected for the junior national team.
Team-mate Miller had been favourite to add a fourth Paralympic gold medal to his collection after successes in Atlanta, Sydney and Athens.
But the Gateshead Harrier, who has cerebral palsy, could not surpass Idoudi's record-breaking throw.
Earlier, David Weir qualified for his fourth Paralympic final as he eased through to Tuesday's T54 1500m final.
Weir has won gold, silver and bronze in the 800m, 400m and 5,000m and having progressed to the 1500m final and the prospect of Wednesday's marathon, it has been a busy few days.
Just 10 hours after being presented his 800m gold medal, the 29-year-old was second in his semi-final, admitting he was exhausted after 11 races in eight days.
Over the weekend, the Surrey athlete was initially denied 800m gold, with Australian rival Kurt Fearnley later withdrawing his appeal over a lanes mix-up.
Weir admitted he considered leaving Beijing, but was happy to have made Tuesday's 1500m final.
"I'm just glad to make it through," he said, with Thailand's Prawat Wahoram, the 5,000m champion, the fastest qualifier.
"I felt comfortable out there, but I am tired."
Shelly Woods, 5,000m bronze medallist, progressed to the 1500m final with a season's best time in her heat.
Graeme Ballard, bronze medallist in Athens, had to settle with sixth in the final of the 200m T36 final.
"I am a little disappointed. I got my head down but on the day it wasn't good enough. There's always London," he said, after clocking 26.69s
Another Brit in action was Tracey Hinton who ran a season's best of 26.58s to qualify for the T11 200m final on Tuesday.
Libby Clegg qualified for the T12 200m final, while Michael Churm qualified for the T37 200m final.