Simmonds is set to make her Paralympic debut in Beijing
British Swimming has nominated 36 swimmers for the GB team for this September's Beijing Paralympics.
The team features a mix of youth and experience from 13-year-old Eleanor Simmonds up to Jim Anderson, 45, who won four golds in Athens in 2004.
Team GB topped the swimming medal standings at the Athens Paralympics with 52 medals, including 16 golds.
They then repeated the feat again at the 2006 World Championships in Durban, South Africa.
Athens Paralympic champions Dave Roberts, Sascha Kindred, Nyree Lewis, Natalie Jones and Andrew Lindsay have been nominated as they seek to retain their titles.
"I think the experience I have gained from the previous Games will help this year," said Kindred, who won gold in the SM6 200 IM and SB7 100m breaststroke in Athens and who will be appearing in his fourth Paralympics in Beijing.
"My first Games in Atlanta was a real shock and I didn't know how to prepare myself for competition but now I know how to stay focused on the task in hand.
"I am looking forward to being able to pass on my knowledge and experience to the younger athletes."
There are also set to be 15 Paralympic debutants, including the likes of world record holders Simmonds, Sam Hynd and Jonathan Fox and European record holders Heather Frederiksen, Stephanie Millward and Louise Watkin.
Watkin said: "I know a Paralympics will be like nothing I have ever been to before but I think I will be able to stay focused and do the best that I can."
Dave Roberts and Matt Walker celebrate their medals in Athens
British Swimming national performance director Tim Reddish said: "The team has a good mix of youth and experience which will benefit all of our athletes, coaches and support staff.
"The average age of this squad is younger than the one that competed in Athens and this demonstrates that the systems and programmes that we have in place are working well.
"Our athletes and their coaches now need to focus upon their preparations for Beijing to continue improving and if they succeed in this I can see them being able to get in the hunt for medals at the Beijing Paralympic Games."
ParalympicsGB chief executive Phil Lane, said: "Swimming has traditionally been one of the most successful Paralympic sports in terms of medals at previous Games.
"The number of emerging youngsters that have been nominated for their first Paralympics is testament to how successfully British Swimming nurture and develop new talent.
"But it's also exciting to see so many established Paralympians returning to the ParalympicsGB squad to defend the titles won in Athens."
The Paralympic swimming events take place at the National Aquatics Centre, nicknamed the Water Cube, from 7-15 September.
GB squad nominations
Men: James Anderson (Broxburn), James Crisp (Nottingham), Gareth Duke (Cwmbran), Graham Edmunds (Swansea), David Ellis (Derbyshire), Jonathan Fox (Cornwall), Sean Fraser (Midlothian), Sam Hynd (Mansfield), Sascha Kindred (Hereford), Dervis Konuralp (Hackney), Andrew Lindsay (Cowdenbeath), Simon Miller (Manchester), David Roberts (Cardiff), Anthony Stephens (Swansea), Matt Walker (Stockport), Robert Welbourn (Swansea), Matt Whorwood (Newquay).
Women: Claire Cashmore (Kidderminster), Emma Cattle (Bedfordshire), Jenny Coughlin (Swansea), Heather Frederiksen (Leigh), Kate Grey (Bristol), Rhiannon Henry (Bridgend), Charlotte Henshaw (Mansfield), Liz Johnson (Swansea), Natalie Jones (Manchester), Rachael Latham (Wigan), Nyree Lewis (Hereford), Mhairi Love (Lanarkshire), Stephanie Millward (Chippenham), Eleanor Simmonds (Swansea), Elizabeth Simpkin (Southport), Lauren Steadman (Cambridgeshire), Louise Watkin (Surrey), Danielle Watts (Oxford), Fran Williamson (Cambridge).
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