The Vikings and Saints clashed in the NFC Championship game last season
Live coverage of NFL games returns to BBC Radio 5 Live Sports Extra for the 2010 campaign.
During the season the BBC will broadcast more games than ever before, with weekly commentaries all the way through to Super Bowl XLV in Dallas in February 2011.
Double-header shows will be aired later in the campaign.
Coverage begins in the early hours of Friday 9 September when the New Orleans Saints take on the Minnesota Vikings.
For commentators Darren Fletcher and Greg Brady it will be a return to the Louisiana Superdome to call a repeat of the 2009 NFC Championship Game.
Other live commentaries during the 2010 season include Donovan McNabb's eagerly-awaited return to Philadelphia as the Washington Redskins take on the Eagles on October 3 and the International Series clash between the San Francisco 49ers and Denver Broncos at Wembley Stadium on October 31.
During the campaign the BBC will broadcast more games than ever before, with double-header shows being aired later in the season.
"We are delighted to be entering a second season of live weekly NFL action on BBC Radio in 2010," said NFL UK managing director Alistair Kirkwood.
"The NFL was very pleased with the community of listeners the show built last season and look forward to increased coverage all the way up to the Super Bowl in February."
There will be additional live commentaries in November and December, as well as every round of the post-season, including the Super Bowl.
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