Jones is still hoping to qualify in the 200m and long jump
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Marion Jones will not defend her Olympic 100m title after finishing fifth at the US trials.
Jones, currently under investigation by the US Anti-Doping Agency, clocked 11.14 seconds in a race won by LaTasha Colander in 10.97.
The 29-year-old refused to comment to waiting journalists, saying she would rather "spend the time with my son."
Jones will still try and qualify for the 200m, in which she is also reigning champion, and the long jump.
Chryste Gaines, one of six athletes competing at the trials while doping appeals are pending, was eliminated at the semi-final stage of the 100m.
Jones' boyfriend, Tim Montgomery - like Gaines awaiting a hearing at the Court of Arbitration for Sport - reached the semi-finals of the 100m on Saturday.
Montgomery, the world record holder, finished fourth in his heat in a time of 10.16 seconds.
Reigning Olympic champion Maurice Greene won his heat in 10.06 seconds but was only the fourth-fastest semi-finalist.
Shawn Crawford, who has the best time in the world this year, set the pace by winning
his heat in 10.00.