Colin Montgomerie led out Europe on the last day and completed his eighth straight singles victory, with another win over David Toms.
Tiger Woods also won to finish as the US's top scorer with three points out of five, but some of the less illustrious members of his team could not cope.
Darren Clarke completed an emotional 3&2 win against Vaughn Taylor before Sweden's Henrik Stenson sealed overall victory against Brett Wetterich.
Sergio Garcia and Lee Westwood top-scored for Europe with four points but courageous Clarke was the enduring image of the event.
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