Tiger Woods says anyone who tests positive under golf's new doping rules deserves to pay a heavy price.
Woods says golf's culture of honesty would prove important
The World Golf Foundation has drawn up a list of testing procedures and banned substances, instead of adopting the World Anti-Doping Agency's (Wada) list.
The world number one said he did not know of anyone taking drugs but backed tough measures should they be found.
"Given how honourable our sport is and always has been, I think the penalty has got to be significant," he said.
The US Tour says it will not disclose the full list of banned substances until it can share the information with the players.
Tour commissioner Tim Finchem said precise details of the programme are being sorted out but testing could begin as early as the spring.
Two classes of drugs on the Wada list - Glucocorticosteroids and Beta-2-Agonists - have been left off golf's banned substance list because they are not believed to enhance a golfer's performance and would cause an administrative burden.
Earlier this year at the Open, nine-times major winner Gary Player sparked controversy by claiming he knew "for a fact" that players were taking drugs, and also said some had even confessed to him.
So far, there has been no significant evidence to back up his allegations.
Woods said he hoped the threat of reputations being damaged in such an honour-based sport would put golfers off getting involved in drugs.
"I think it would be very disappointing if it did happen," he said.
"I think that person's reputation would be obviously damaged pretty significantly."