World Cup favourites Spain suffered a shock defeat by Switzerland as South Africa 2010 served up its first major upset.
The European champions enjoyed almost total control of the game in Durban but were wasteful in front of goal and went behind after 52 minutes when a long ball eventually found its way through to Gelson Fernandes, who, after a series of errors, bundled it into the net.
With Barcelona trio David Villa, Andres Iniesta and Xavi unable to conjure a breakthrough, coach Vicente Del Bosque threw on Fernando Torres, Jesus Navas and Pedro, but to no avail as the Spanish slumped to only their second defeat in 49 games.
The result piles pressure on Spain, who were widely-tipped to finally end decades of underachievement on the game's biggest stage and Del Bosque's men could now be forced to face Brazil in the second round if they finish Group H as runners-up. Chile beat Honduras 1-0 in the earlier match.
For the unfancied Swiss, it was a historic first victory over the Spanish and another triumph in the glittering career of their German coach Ottmar Hitzveld.
Del Bosque's men had quickly settled into their rhythmic short passing game and, with Switzerland struggling to get the ball out of their own half, the match came to resemble a training session.
The first real opening fell to Spain right-back Sergio Ramos, who received the ball in space on the right before dragging his shot wastefully wide, much to the anger of his better-placed team-mates Xavi and David Villa.
Moments later, Iniesta slipped a pass through to Gerard Pique, who cut inside his man before firing straight at goalkeeper Diego Benaglio.
The next attack saw David Silva chip a delightful ball over the Switzerland defence for Iniesta, who was brought down on the edge of the area as he tried to get his shot away. Villa fired the resultant free-kick straight at the wall.
The Swiss were forced into a change midway through the half when former Arsenal defender Philippe Senderos limped off with a foot injury and was replaced by Steve Von Bergen.
Lone striker Villa looked skilful and lively, but when he finally found space in the box, he opted to pass, and chipped tamely across the face of goal.
The second half began in a similar vein until the Swiss took the lead with the first real attack of the game.
A long goal-kick was flicked through to Eren Derdiyok, who bundled it past goalkeeper Iker Casillas and the falling Pique to leave former Manchester City midfielder Fernandes with a simple finish.
Spain, who won all 10 of their World Cup qualifiers, looked visibly shaken and Del Bosque responded by sending on Torres and Navas just after the hour mark.
Iniesta and Torres both curled shots wide before former Liverpool midfielder Xabi Alonso almost broke the crossbar with a stunning strike from just outside the area.
With Spain committing more men forward, the game became stretched and Switzerland came within a whisker of taking a 2-0 lead when Derdiyok cut inside Pique and Carles Puyol before flicking a shot which had Casillas beaten but bounced back off the post.
The last 10 minutes were a predictable Spanish onslaught but, with Torres looking rusty on his return from knee surgery, Spain seemed to run out of ideas as their efforts became increasingly desperate.
As it was, Switzerland held firm for a truly memorable victory - their first in a World Cup opener since 1954.
Attempts on target
Attempts off target
Projected table based on current scores
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