Juan Ugarte has left Wrexham after conceding defeat in his battle to overcome a succession of knee injuries.
Ugarte won the LDV Vans Trophy in his first season at Wrexham
Persistent knee and hamstring problems have limited the Basque striker to a handful of substitute appearances over the last two seasons.
Despite undergoing several operations, 27-year-old Ugarte has failed to regain full fitness and has now asked for his Wrexham contract to be cancelled.
"It's sad that he has decided to move on," said manager Brian Little.
"He's a really nice guy who has had a tough period. I myself had to retire from football at a similar age to him.
"I know he has had a load of injury issues, but I would like to wish well and hope that it all works out for him.
"Juan will always be welcome back here at any time and we all look forward to seeing him again at some time in the future."
Ugarte was awarded with a new 18-month contract at the Racecourse in November 2006, despite being sidelined for the previous nine months with a recurrence of an old knee injury.
Further injury problems saw the striker play just 42 minutes of football for the reminder of the 2006/07 season, and his last appearance came as a substitute in Wrexham's 2-1 defeat to Stockport in September.
An astonishing 17 goals in just 23 League One starts made Ugarte an immediate hit with the Dragons fans in his first season at the Racecourse in the 2004/05 season.
He joined Championship side Crewe the following season, but returned to the Racecourse after an unhappy year at Gresty Road - which included brief loan spells with Wrexham, which were cut short by injury.
Ugarte has stepped up his rehabilitation work in January, but another set-back has convinced him to call time on his career.