West Ham director Trevor Brooking has confirmed the club would be interested in moving into a new Olympic Stadium built if London wins the 2012 Games.
West Ham could leave Upton Park
The Hammers and Tottenham have been targeted by bid organisers as possible occupants of the new venue to avoid any "white elephants" after the event.
"It is a realistic opportunity," Brooking told BBC Sport.
"I believe the chairman of the club has had preliminary talks and the interest is there."
Brooking added: "Stratford is a large catchment area for the club and it would be very wrong of us not to listen.
"A lot of the talks so far have just been preparatory and from the club's point of view it is still seven years away.
"But if the London bid is successful more meaningful discussions would have to take place."
Brooking added that West Ham are not actively seeking to quit Upton Park, which was expanded to a 36,000 capacity two years ago while the club was still in the Premiership.
Plans to finish the last part of the stadium have had to be shelved indefinitely while the club struggles with the financial implications of relegation.
The proposed Olympic Stadium would hold 80,000 spectators, although it is likely the design options would include provision for reducing future capacity.
"It can change from 80,000 for the ultimate tenant," confirmed London 2012 bid chief Barbara Cassani. "There will be no white elephants in this bid."