Tottenham's Uefa Cup hopes have been dealt a blow by news that keeper Paul Robinson will miss the final two Premiership games.
England keeper Robinson injured a knee when colliding with Darius Vassell in the 5-1 win over Aston Villa.
Head of medical services Dr Charlotte Cowie confirmed to Spurs' website that a scan showed ligament damage.
Czech keeper Radek Cerny, who replaced Robinson against Villa, will make his first start for Spurs at Middlesbrough.
Spurs were hopeful Robinson would be fit for their run-in after initial tests suggested the England keeper's injury was not serious.
Manager Martin Jol had said Robinson suffered a dead leg and was confident he would be fit for the last two games.
"Everyone was confident he would make it after the Aston Villa game. Now there is nothing we can do about it," said Jol.
"I could have decided to play him but the medical team said that because it is a tear in his knee it was best not to risk him.
"I don't think it will be a problem for the new keeper behind the defence. Radek is very experienced and I have no doubts about him.
"He has even more experience than Robinson in Europe. He has played plenty of games for his previous club.
"Hans Segers has been impressed with him in the reserves. He has been laughing in training and looks like he's looking forward to it.
"We will manage without Paul. I thought we would really struggle when Michael Brown got injured - but we didn't.
"I thought we would have difficulty when we lost Noureddine Naybet. Then Michael Dawson came in and did well."
Czerny, 29, is on loan from Slavia Prague.
Seventh-placed Spurs travel to Middlesbrough - with whom they are level on 51 points - and face Blackburn at home as they chase a Uefa Cup spot.
The extra place in Europe for English clubs is as a result of league champions Chelsea winning the Carling Cup, while Arsenal and Manchester United are contesting the FA Cup final - having already qualified for the Champions League.