Rooney is also set to sit out the Manchester derby on 10 November as well as England's game with France a week later.
His last appearance was as a late substitute in
United's 2-2 draw with West Brom
on 16 October when he cut the same out-of-sorts figure he has done since the end of last season.
Rooney, whose last goal from open play came in March, struggled at the World Cup in the summer and has scored only once - a penalty in the 3-0 win over West Ham in August - in the Premier League so far this season.
He was initially expected to be ruled out for three weeks, raising the possibility of him returning for United's trip to local rivals Manchester City.
But Ferguson recently said: "No chance. Any player who has been out for a few weeks - you want them 100% and not breaking down."
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