The NFL finance committee will review Tampa Bay Buccaneers owner Malcolm Glazer's bid to assume full control of Manchester United for £790m.
Glazer is set to buy a majority share at Old Trafford but there are growing concerns in the US about how he intends to pay back the £540m he has borrowed.
NFL spokesman Greg Aiello confirmed there is a possibility Glazer intends to use the Buccaneers as collateral.
"The committee is just going to look for issues of concern," Aiello said.
Glazer bought the Buccaneers for £125m a decade ago and transformed the team, leading them to the Super Bowl in 2003.
Last year, Forbes magazine valued the Florida team at £421m ($779m) which would go some way to financing Glazer's move for Manchester United.
The Glazer family have pledged not to sell the Buccaneers and the team's general manager Bruce Allen insisted affairs at Old Trafford, "won't change anything we've been doing".
He added cheerfully: "Throughout the world, they're going to be talking about the Tampa Bay Buccaneers."