Macclesfield manager Paul Ince has released five players at the end of his first season in charge at Moss Rose.
Andrew Smart, Colin Heath, Marvin McDonald, Rob Scott and Robbie Doyle have all left the club.
Ronayne Benjamin, who was on non-contract terms, has also departed and Martin Bullock has joined Wycombe.
Twelve players have been offered new deals including Carl Regan, John Miles, Alan Navarro, Kevin McIntyre, Jon Brain, Izak Reid and Jimmy McNulty.
Dave Morley, Matty McNeil, Andrew Teague and James Jennings are the other players considering new contracts.
Mick Jeffries and Matthew Flynn have both been offered six-month deals after stepping up from the youth team.
But previous loan signings Matthew Tipton, Isaiah Rankin, Ashan Holgate and Simon Wiles have all returned to their parent clubs.
Ince told his club's website: "The core of the squad from last season has been offered new deals and we are hopeful that most of them will accept the terms we have to put to them.
"Unfortunately we have had to let some players go. That is never nice but it is the reality of football.
"And in doing so it provides me with some scope to strengthen the squad in key areas and improve our chances of success next season."