However, their involvement in that tournament was limited to home-and-away defeats by Slovenians NK Maribor before this season's domestic campaign had begun.
A frustrating start to the 2010/11 season, where Hibs have lost four out of seven matches and sit a point above bottom club St Mirren, was compounded by a 3-1 defeat by Kilmarnock in the Co-operative Insurance Cup.
There were a number of departures at the club over the summer, among them goalkeeper Yves Ma-Kalambay and Abdessalam Benjelloun.
But the sale of striker Anthony Stokes to Celtic at the end of August for about £800,000 would have been a blow to Hughes, for the Irishman, with 23 goals, was the club's top scorer last season.
Hughes signed a replacement in Darryl Duffy, on loan from Bristol Rovers. The former Scotland Under-21 international has made three substitute appearances and has yet to score for the Easter Road side.
Whoever replaces Hughes will have at his disposal recent signings Edwin de Graaf from Breda, Middlesbrough's Jonathan Grounds, Utrecht defender Francis Dickoh and striker Valdas Trakys.
Interim appointments aside - and there have been three of those in Donald Park, Mark Proctor and Tommy Craig - Hibs have had seven managers in 10 years.
Their three most recent managerial appointments have gone to former players - Hughes, Mixu Paatelainen and John Collins.
Since Alex McLeish left Easter Road in December 2001, Franck Sauzee, Bobby Williamson and Tony Mowbray have also been in the Leith hot seat.
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