Cambridge United have terminated the contract of manager Herve Renard following the club's disappointing defeat at Oxford United on Saturday.
Renard has left the club in a poor position in the league
Assistant boss Ricky Duncan will be put in caretaker charge of the club, who are next to bottom of League Two.
Chairman Gary Harwood told the club's website: "It was very amicable and it is something we didn't want to do.
"But we have not got time for Renard's philosophy to flow through to our team, given where we are in the league."
Renard took over from fellow Frenchman Claude Le Roy in the summer but the loss to Oxford was Cambridge's eighth in nine games.
Meanwhile, Harwood is now keen to speak to former U's striker Dion Dublin about the possibility of replacing Renard.
CAMBRIDGE UNDER RENARD
League & Cup record:
Goals for: 20
Goals against: 32
Dublin, now 35, spent four successful seasons at the Abbey Stadium between 1988 and 1992 before joining Manchester United for £1m - which remains Cambridge's record sale.
He is currently playing in central defence for Championship side Leicester City, but may be keen to leave after new boss Craig Levein made it clear he was no longer a first-choice forward at the Walkers Stadium.
Harwood continued: "If Dion is interested, we would certainly be interested in hearing from him.
"Dion had a memorable time here, and I would certainly not rule out holding an interview with him to see what he has got to say.
"His appointment would certainly be popular and he would also add valuable experience - and possibly get us a few goals while he is at it.
"At the moment though, I am just terribly deflated at the situation because Herve was one of the best people I have ever worked with in football and he will remain a good friend of mine."