Birmingham boss Steve Bruce has been refused special dispensation to play his son Alex against Newcastle.
The Blues are missing 10 players ahead of Saturday's game and recalled Alex, 21, from a loan spell at Tranmere.
But the Premier league ruled that the player is ineligible to represent the Blues after returning a month early.
It is yet another setback for depleted Birmingham, who are deep in relegation trouble - just one point above bottom club Sunderland.
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