The latest casualties add to a growing injury list at Arsenal that also includes striker Eduardo da Silva, who was not fit enough to be in the squad to face Stoke.
However, Wenger feels the the Croatia international will shrug off the thigh problem to return next week.
The Gunners, who face Olympiacos in their final Champions League group game in Athens on Wednesday, are already without Robin van Persie (ankle), Nicklas Bendtner (groin), Gael Clichy (back), Theo Walcott (hamstring), Abou Diaby (calf), Kieran Gibbs (ankle) and Johan Djourou (knee).
"We pick up more injuries than the other big teams, that is true," added Wenger.
"You cannot say there is not a reason for it but we have not found it yet.
"It's the worst season for injuries for us. And they are all in the same area - in the offensive side. Last year it was in the defensive side."
Arsenal are already into the knockout stages in Europe and Wenger will not be taking any chances with any of his experienced players ahead of Sunday's crucial Premier League clash with Liverpool.
I have seen things about Middlesbrough, Celtic and Rangers being interested and there may be others, but a Premier League side would be better
Arsenal midfielder Jack Wilshere on a potential loan move
Instead, Wenger is likely to use many of the youngsters who helped the Gunners reach the quarter-finals of the Carling Cup.
"In the competition as a whole this season, the boys did really well and I am extremely proud of them. I will give some of them an opportunity on Wednesday, for many reasons," Wenger explained.
"At the moment we have so many players injured that we cannot take any gambles; also you must give players a breather when you can."
Jack Wilshere is one of those likely to come in to the Gunners' line-up, but the England Under-21 star admits he would consider a loan deal to gain more first-team experience this season.
The 17-year-old midfielder, who turns 18 on 1 January, has made only five appearances this season, and said: "I would think about a loan move but I think it would have to be in the Premier League.
"Not that the Championship is a bad league at all, but it might suit me differently.
"I have seen things about Middlesbrough, Celtic and Rangers being interested and there may be others, but a Premier League side would be better.
"I would, of course, rather stay and be involved at Arsenal though, so we will see what happens."
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